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Trial record 1 of 1 for:    NCT02786654
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β Blocker Use and Mortality in Hospital Survivors of Acute Myocardial Infarction Without Heart Failure

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ClinicalTrials.gov Identifier: NCT02786654
Recruitment Status : Completed
First Posted : June 1, 2016
Last Update Posted : June 6, 2016
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The aim of the study is to investigate the association between the use of β blockers and mortality among hospital survivors of acute myocardial infarction without heart failure.

Condition or disease
Acute Myocardial Infarction

Study Design

Study Type : Observational [Patient Registry]
Actual Enrollment : 179810 participants
Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 6 Years
Official Title: β Blocker Use and Mortality in Hospital Survivors of Acute Myocardial Infarction Without Heart Failure
Study Start Date : January 2007
Primary Completion Date : June 2013
Study Completion Date : June 2013

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts


Outcome Measures

Primary Outcome Measures :
  1. All cause mortality [ Time Frame: 1 year ]

Secondary Outcome Measures :
  1. All cause mortality [ Time Frame: 6 months ]
  2. All cause mortality [ Time Frame: 30 days ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 100 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The study population comprised of 179,810 in hospital survivors of acute myocardial infarction without heart failure recorded in the Myocardial Ischaemia National Audit Project registry between 2007 and June 2013
Criteria

Inclusion Criteria:

  • acute myocardial infarction patients only
  • aged 18 to 100 years

Exclusion Criteria:

  • other final diagnosis besides acute myocardial infarction
  • died in-hospital
  • patients with missing mortality data
  • aged > 100
  • patients with previous acute myocardial infarction or angina
  • patients who have received coronary interventions before
  • patients with heart failure
  • patients with β blocker prior use
  • patients contraindicated for β blocker use
  • patients with use of a loop diuretic
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02786654


Locations
United Kingdom
University of Leeds
Leeds, United Kingdom, LS2 9JT
Sponsors and Collaborators
University of Leeds
Investigators
Principal Investigator: Chris P Gale, FRCP University of Leeds
More Information

Responsible Party: Tatendashe Bernadette Dondo, Research assistant, University of Leeds
ClinicalTrials.gov Identifier: NCT02786654     History of Changes
Other Study ID Numbers: PG/13/81/30474BB
First Posted: June 1, 2016    Key Record Dates
Last Update Posted: June 6, 2016
Last Verified: June 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Keywords provided by Tatendashe Bernadette Dondo, University of Leeds:
Acute myocardial infarction
mortality
evidence-based care
Myocardial Ischaemia National Audit Project
β blockers

Additional relevant MeSH terms:
Heart Failure
Infarction
Myocardial Infarction
Heart Diseases
Cardiovascular Diseases
Ischemia
Pathologic Processes
Necrosis
Myocardial Ischemia
Vascular Diseases
Adrenergic beta-Antagonists
Adrenergic Antagonists
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs