Quantifying Quadriceps Atrophy Following Tibial Plateau Fracture
|ClinicalTrials.gov Identifier: NCT02781623|
Recruitment Status : Enrolling by invitation
First Posted : May 24, 2016
Last Update Posted : July 11, 2017
|Condition or disease||Intervention/treatment|
|Study Type :||Observational|
|Estimated Enrollment :||10 participants|
|Official Title:||Quantifying Quadriceps Atrophy Following Tibial Plateau Fracture|
|Study Start Date :||October 2015|
|Estimated Primary Completion Date :||October 2019|
|Estimated Study Completion Date :||October 2019|
An MRI will be conducted pre-operatively, 3 months post-operatively, and 1 year post-operatively.
- Cross-sectional area (CSA) calculations [ Time Frame: 1 Year ]From the axial images obtained from the MRI for each leg, outlines of each muscle in the quadriceps femoris muscle group will be traced and used to calculate.
- Quadriceps muscle strength [ Time Frame: One Year ]This will be measured by the highest knee-extension torque over six repetitions for each leg.
- Muscle Volume [ Time Frame: One Year ]This will be measured by the sum of the CSAs (Cross Sectional Areas) of each image times the thickness (10mm) and interslice gap (10mm) of each section
- Pain Level [ Time Frame: One Year ]This will be measured by the Short Musculoskeletal Function Assessment Questionnaire (SMFA)
- Isokinetic Knee-Extension Strength Test [ Time Frame: One year ]This test will be conducted on both legs to compare the physical strength of the injured leg with the non-injured leg.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02781623
|United States, New York|
|New York University Langone Medical Center|
|New York, New York, United States, 10016|
|Principal Investigator:||Kenneeth Egol, MD||New York University School of Medicine|