Quantifying Quadriceps Atrophy Following Tibial Plateau Fracture
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|ClinicalTrials.gov Identifier: NCT02781623|
Recruitment Status : Enrolling by invitation
First Posted : May 24, 2016
Last Update Posted : June 7, 2018
|Condition or disease||Intervention/treatment|
|Study Type :||Observational|
|Estimated Enrollment :||10 participants|
|Official Title:||Quantifying Quadriceps Atrophy Following Tibial Plateau Fracture|
|Study Start Date :||October 2015|
|Estimated Primary Completion Date :||October 2019|
|Estimated Study Completion Date :||October 2019|
An MRI will be conducted pre-operatively, 3 months post-operatively, and 1 year post-operatively.
- Cross-sectional area (CSA) calculations [ Time Frame: 1 Year ]From the axial images obtained from the MRI for each leg, outlines of each muscle in the quadriceps femoris muscle group will be traced and used to calculate.
- Quadriceps muscle strength [ Time Frame: One Year ]This will be measured by the highest knee-extension torque over six repetitions for each leg.
- Muscle Volume [ Time Frame: One Year ]This will be measured by the sum of the CSAs (Cross Sectional Areas) of each image times the thickness (10mm) and interslice gap (10mm) of each section
- Pain Level [ Time Frame: One Year ]This will be measured by the Short Musculoskeletal Function Assessment Questionnaire (SMFA)
- Isokinetic Knee-Extension Strength Test [ Time Frame: One year ]This test will be conducted on both legs to compare the physical strength of the injured leg with the non-injured leg.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02781623
|United States, New York|
|New York University Langone Medical Center|
|New York, New York, United States, 10016|
|Principal Investigator:||Kenneeth Egol, MD||New York University School of Medicine|