Motor Development of Children That Have Surgery as Newborns for Complex Congenital Heart Disease
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Infants requiring surgery in the neonatal period for complex congenital heart diseases are at risk for developmental problems. For infants with congenital heart diseases with admixture physiology and single ventricles, optimal circulation is associated with signs of adequate systemic perfusion and a systemic arterial oxygen saturation typically between 75% to 90%. Infants are often unable to withstand standardized developmental testing during early infancy due to medical fragility and sternal precautions after surgery. Evaluation of the quality of spontaneous movements and movement variability is a good alternative. The quality of general movements in early infancy is a valid predictor of neurological disorders in high risk infant groups and is assessed with short periods of video-recorded observations. This methodology has yet to be studied in infants with complex congenital heart disease that require surgery as neonates. For older infants, the Infant Motor Profile (IMP) is a promising tool to document developmental outcome.
Motor development at 18 months [ Time Frame: 18 months ]
Comparison of motor development of two groups of infants based on oxygen saturation targets after neonatal surgery using the Infant Motor Profile
Secondary Outcome Measures :
Movement quality from birth to 4 months of age [ Time Frame: 4 months. The infant's general movements are video-recorded three to five times from birth to four month according to this schedule: pre-operation (if possible), hospital discharge, one month of age, two months of age, and three months of age ]
Comparison of the trajectory of movement quality for two infant groups based on video recorded General Movements Assessments for at least three assessment points from birth to 4 months of age
Concurrent validity [ Time Frame: 18 months ]
Assess concurrent validity of the Infant Motor Profile total score and performance score with the Alberta Infant Motor Scales at 6, 12, and 18 months, and the Bayley Scales of Infant Development (3rd edition) motor composite score at 18 months
Cognitive and language development at 18 months [ Time Frame: 18 months ]
Comparison of the two infant groups based on the cognitive and language composite scores of the Bayley Scales of Infant Development (3rd edition)
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Layout table for eligibility information
Ages Eligible for Study:
up to 24 Months (Child)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Consecutive infant sampling of infants with complex congenital heart diseases
Infants diagnosed with complex congenital heart diseases that require surgery during the neonatal period, ages 0-30 days
Surgical care at Advocate Christ Medical Center/Advocate Children's Hospital, Oak Lawn, Il