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Antimicrobials Stewardship by Pharmacist

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ClinicalTrials.gov Identifier: NCT02768454
Recruitment Status : Unknown
Verified May 2016 by National Taiwan University Hospital.
Recruitment status was:  Active, not recruiting
First Posted : May 11, 2016
Last Update Posted : May 13, 2016
Sponsor:
Information provided by (Responsible Party):
National Taiwan University Hospital

Brief Summary:
To study the outcome of antibiotics stewardship

Condition or disease Intervention/treatment
Infection Drug: medical review of controlled broad-spectrum antibiotics

Detailed Description:
Retrospective cohort study by medical review and evaluation of broad-spectrum antibiotics to determine how appropriately it was bing used.

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Study Type : Observational
Estimated Enrollment : 200 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Appropriate Use of Controlled Broad-spectrum Antimicrobials by Establish Stewardship and Execute by Antibiotic Pharmacist
Study Start Date : September 2015
Estimated Primary Completion Date : September 2016
Estimated Study Completion Date : September 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Antibiotics

Group/Cohort Intervention/treatment
inpatient under broad-spectrum antibiotics
medical review
Drug: medical review of controlled broad-spectrum antibiotics
medical review of outcome of antibiotics stewardship by pharmacists and infectious disease physicians




Primary Outcome Measures :
  1. The percentage of appropriateness of empirical antibiotics choosing. [ Time Frame: up to 8 weeks ]
    For example,the inappropriate of piperacillin-tazobactam as empirical therapy was numbers of participants with no risk factors of deep tissue infection or DM foot /Number of participants treated with piperacillin-tazobactam for soft tissue infection.

  2. The percentage of appropriateness of de-escalation of therapy. [ Time Frame: up to 8 weeks ]
    For example,continued piperacillin-tazobactam was seen to be inappropriate when microbiologic results and clinical status permit de-escalation.


Secondary Outcome Measures :
  1. Number of adverse events of antibiotics were recorded. [ Time Frame: up to 8 weeks ]


Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 99 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
the investigators randomly do medical chart review of patients received broad-spectrum antibiotics from their hospital systems.
Criteria

inclusion criteria:

  • Inpatient with infectious disease and under broad-spectrum antibiotics

exclusion criteria:

  • Poor prognosis was diagnosed or received conservative therapy only.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02768454


Locations
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Taiwan
National Taiwan University Hospital
Yun-Lin, Dou-Liou, Taiwan, test3
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
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Principal Investigator: Shu-Chen Yang, master National Taiwan University Hospital, Yun-Lin Branch

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Responsible Party: National Taiwan University Hospital
ClinicalTrials.gov Identifier: NCT02768454     History of Changes
Other Study ID Numbers: 201511065RIND
First Posted: May 11, 2016    Key Record Dates
Last Update Posted: May 13, 2016
Last Verified: May 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

Keywords provided by National Taiwan University Hospital:
broad-spectrum antimicrobial
antibiotics pharmacist

Additional relevant MeSH terms:
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Anti-Bacterial Agents
Antibiotics, Antitubercular
Anti-Infective Agents
Antitubercular Agents