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Preemptive and Preventive Use of Paracetamol for Pain Relief After Cesarean Section

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ClinicalTrials.gov Identifier: NCT02714179
Recruitment Status : Completed
First Posted : March 21, 2016
Last Update Posted : March 21, 2016
Sponsor:
Information provided by (Responsible Party):
Ozlem Ozmete, Baskent University

Brief Summary:
The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive versus preventive paracetamol on postoperative pain scores, patient satisfaction, total morphine consumption and the incidence of morphine‑related side effects in patients undergoing cesarean section.

Condition or disease Intervention/treatment Phase
Cesarean Section; Dehiscence Drug: Paracetamol was given intravenously in both group at different times Phase 4

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 54 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Care Provider, Investigator, Outcomes Assessor)
Official Title: A Double Blind Randomised Controlled Trial of Preemptive and Preventive Use of Paracetamol for Pain Relief After Cesarean Section
Study Start Date : May 2015
Actual Primary Completion Date : January 2016
Actual Study Completion Date : January 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cesarean Section

Arm Intervention/treatment
Active Comparator: Group Preemptive (Group PE),
Group I: i.V. paracetamol 1 g (100 ml) was given 30 min before induction of anesthesia.
Drug: Paracetamol was given intravenously in both group at different times
Active Comparator: Group Preventive (Group PV),
Group II: i.V. paracetamol 1 g (100 ml) was given before the end of surgery.
Drug: Paracetamol was given intravenously in both group at different times



Primary Outcome Measures :
  1. Visual analog score (VAS) for pain [ Time Frame: 24 hours ]


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Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

38 weeks pregnancy, elective cesarean section.

-

Exclusion Criteria:

morbid obesity, cardiac failure, depression.


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Responsible Party: Ozlem Ozmete, Medical Doctor, Baskent University
ClinicalTrials.gov Identifier: NCT02714179     History of Changes
Other Study ID Numbers: KA15/80
First Posted: March 21, 2016    Key Record Dates
Last Update Posted: March 21, 2016
Last Verified: March 2016
Additional relevant MeSH terms:
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Acetaminophen
Analgesics, Non-Narcotic
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Antipyretics