UTSW Depression Cohort: A Longitudinal Study of Depression
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02697487|
Recruitment Status : Active, not recruiting
First Posted : March 3, 2016
Last Update Posted : October 2, 2019
|Condition or disease||Intervention/treatment|
|Depression Other Diagnoses, Comorbidities, and Complications||Other: No treatment|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||100000 participants|
|Official Title:||UTSW Depression Cohort: A Longitudinal Study of Depression|
|Study Start Date :||February 2016|
|Estimated Primary Completion Date :||February 2026|
|Estimated Study Completion Date :||February 2027|
This is a longitudinal observational study involving individuals who are depressed, depressed with other comorbidities and non-depressed individuals. The primary aim of this study is to describe the longitudinal course of illness and real world treatment outcomes for depressed patients receiving routine care from their providers. Health outcomes and biospecimens along with the functional and economic burden of depression will be characterized and compared amongst three groups: (1) depressed patients, (2) depressed patients with comorbid illnesses, and (3) non-depressed patients.
Other: No treatment
This is an observational study with no intervention.
- Longitudinal changes in depression severity as measured by 9-item Patient Health Questionnaire [ Time Frame: 10 years ]
- Comparison of longitudinal changes in functioning as measured by 5-item Work and Social Adjustment Scale in participants with and without depression. [ Time Frame: 10 years ]
Biospecimen Retention: Samples With DNA
Biospecimens being studied is as follows:
- Normal Tissue
- Clinical waste products to include surgical waste tissue samples, placenta samples, and biopsy samples.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02697487
|United States, Texas|
|University of Texas Southwestern Medical Center|
|Dallas, Texas, United States, 75390|
|Principal Investigator:||Madhukar Trivedi, MD||University of Texas Southwestern Medical Center|