The Chinese Hypertrophic Cardiomyopathy Study(CHCS) (CHCS)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02696135|
Recruitment Status : Recruiting
First Posted : March 2, 2016
Last Update Posted : March 27, 2018
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||3000 participants|
|Official Title:||The Chinese Hypertrophic Cardiomyopathy Study(CHCS)|
|Actual Study Start Date :||March 23, 2011|
|Estimated Primary Completion Date :||December 31, 2025|
|Estimated Study Completion Date :||December 31, 2028|
Individuals with an unexplained maximal left ventricle wall thickness ≥15 mm on echocardiography and/or cardiac magnetic resonance imaging or or ≥13 mm for individuals with family history of HCM, in the absence of other cardiac or systemic diseases capable of producing that magnitude of cardiac hypertrophy.
- Cardiovascular deaths [ Time Frame: an average of 2 years ]Including SCD and deaths due to heart failure and stroke.
- all-cause mortality [ Time Frame: an average of 2 years. ]deaths due to all causes.
- Heart failure [ Time Frame: an average of 2 years ]Progress to level III or IV in New York Heart Association class.
- Stroke [ Time Frame: an average of 2 years ]including cerebral infarction and hemorrhage
- Malignant arrhythmia [ Time Frame: an average of 2 years ]The incidence rate of malignant arrhythmia
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02696135
|Contact: Song Lei, MD.&ph.Dfirstname.lastname@example.org|
|Contact: Song Lei, MD.&ph.Demail@example.com|
|Beijing, Beijing, China, 100037|
|Contact: Lei Song, MD.& PhD. 86-13810532620 firstname.lastname@example.org|
|Contact: Lei Song, MD.& PhD. 86-18600197655 email@example.com|
|Principal Investigator:||Song Lei, MD.&ph.D||Fuwai Hospital|