Chile Biliary Longitudinal Study
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|ClinicalTrials.gov Identifier: NCT02692911|
Recruitment Status : Recruiting
First Posted : February 26, 2016
Last Update Posted : March 20, 2019
The gallbladder is a small organ below the liver. Gallbladder cancer is a leading cause of cancer death among women in Chile. Chile also has among the highest rates of gallbladder cancer and death in the world. Researchers in a high-risk region of Chile want to find out more about this type of cancer. They especially want to know how inflammation affects the way it develops.
To better understand the causes of gallbladder diseases and factors that may be associated with them.
Women ages 50 74 with gallbladder cancer who are covered by the Chilean national health system.
Other people over age 21 with gallbladder disease.
Healthy adults over age 21.
Participants may be screened with an ultrasound. They may be asked questions about their health.
Participants will have an ultrasound of the abdomen. This can be done at the study clinic or in the hospital or at home. The ultrasound uses sound waves to take pictures of the gallbladder.
Participants will have a physical exam.
Participants will have their mouths looked at for tooth loss, dentures, and gum redness.
Participants will give a blood sample or saliva sample.
Participants will be asked for access to their medical history. They may be asked to allow researchers to keep any samples taken during gallbladder surgery.
Participants will answer questions about their medical history. This will include illnesses, surgeries, medicine use, and family history. It will also include diet and lifestyle habits, such as places where they have lived and worked.
Some participants will have 3 follow-up visits over 6 years.
|Condition or disease|
|Gallbladder Cancer Nutritional and Metabolic Diseases|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||35000 participants|
|Official Title:||Chile Biliary Longitudinal Study|
|Study Start Date :||February 25, 2016|
|Estimated Primary Completion Date :||December 31, 2023|
|Estimated Study Completion Date :||January 31, 2026|
Women with gallstones
Women aged 50-74 with gallstones
- Cancer/precancer [ Time Frame: during course of the study ]Our major exposures of interest are patterns, levels, and changes in inflammatory markers and ultrasound characteristics, with Gallbladder Dysplasia and Cancer as the primary outcome of interest.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02692911
|Contact: Jill E. Koshiol, M.D.||(301) email@example.com|
|Hospital Regional de Talca||Recruiting|
|Universidad Catolica del Maule||Recruiting|
|Hospital Regional de Temuco||Recruiting|
|Principal Investigator:||Jill E. Koshiol, M.D.||National Cancer Institute (NCI)|