Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.
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|ClinicalTrials.gov Identifier: NCT02646553|
Recruitment Status : Unknown
Verified August 2017 by Haukeland University Hospital.
Recruitment status was: Recruiting
First Posted : January 5, 2016
Last Update Posted : August 16, 2017
|Condition or disease||Intervention/treatment|
|Cushings Syndrome||Other: Children refered to the obesity clinic|
the investigators have collected saliva samples morning and late evening for cortisol measurements in a total of 330 children ( 660 samples) in the age from 4 to 16 years ols. This samples are going to be used to define a reference range for saliva cortisol in children.
The investigators are then collecting 24 hour urine and saliva samples ( morning and late evening) from children at the obesity clinic Haukeland University hospital for verification of the reference range , and to estimate if the test is good enough to identify the patients that have Cushings syndrome.
Since the diagnose is very seldom in children, we will get help from a 3. line referral center in London to include patients with true Cushings syndrome.
|Study Type :||Observational|
|Estimated Enrollment :||70 participants|
|Official Title:||Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.|
|Study Start Date :||May 2012|
|Estimated Primary Completion Date :||April 2019|
|Estimated Study Completion Date :||April 2019|
Children refered to the obesity clinic.
All children refered to the obesity clinic for examination and optionally treatment are invited.
Other: Children refered to the obesity clinic
Compere if urine cortisol is as good as saliva cortisol as a screening for hypercortisolism in children.
- Number of patients with positive saliva cortisol measurement, not having Cushings syndrome. [ Time Frame: 2 years ]Number of patients
- Number of patients With negative saliva cortisol measurement , having Cushings syndrome. [ Time Frame: 2 years ]Number of patients
Biospecimen Retention: Samples Without DNA
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02646553
|Contact: Grethe Åstrøm Ueland, MD||90950021 ext +firstname.lastname@example.org|
|Contact: Gunnar Mellgren, Prof.||55974366 ext +email@example.com|
|Principal Investigator:||Grethe Åstrøm Ueland, MD||Haukeland University Hospital|