Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.
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|ClinicalTrials.gov Identifier: NCT02646553|
Recruitment Status : Recruiting
First Posted : January 5, 2016
Last Update Posted : August 16, 2017
|Condition or disease||Intervention/treatment|
|Cushings Syndrome||Other: Children refered to the obesity clinic|
the investigators have collected saliva samples morning and late evening for cortisol measurements in a total of 330 children ( 660 samples) in the age from 4 to 16 years ols. This samples are going to be used to define a reference range for saliva cortisol in children.
The investigators are then collecting 24 hour urine and saliva samples ( morning and late evening) from children at the obesity clinic Haukeland University hospital for verification of the reference range , and to estimate if the test is good enough to identify the patients that have Cushings syndrome.
Since the diagnose is very seldom in children, we will get help from a 3. line referral center in London to include patients with true Cushings syndrome.
|Study Type :||Observational|
|Estimated Enrollment :||70 participants|
|Official Title:||Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.|
|Study Start Date :||May 2012|
|Estimated Primary Completion Date :||April 2019|
|Estimated Study Completion Date :||April 2019|
Children refered to the obesity clinic.
All children refered to the obesity clinic for examination and optionally treatment are invited.
Other: Children refered to the obesity clinic
Compere if urine cortisol is as good as saliva cortisol as a screening for hypercortisolism in children.
- Number of patients with positive saliva cortisol measurement, not having Cushings syndrome. [ Time Frame: 2 years ]Number of patients
- Number of patients With negative saliva cortisol measurement , having Cushings syndrome. [ Time Frame: 2 years ]Number of patients
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02646553
|Contact: Grethe Åstrøm Ueland, MD||90950021 ext +email@example.com|
|Contact: Gunnar Mellgren, Prof.||55974366 ext +firstname.lastname@example.org|
|Haukeland University Hospital||Recruiting|
|Bergen, Norway, 5021|
|Contact: Grethe Ueland, MD +4790950021 email@example.com|
|Contact: Gunnar Mellgren, MD +4755974366 firstname.lastname@example.org|
|Principal Investigator:||Grethe Åstrøm Ueland, MD||Haukeland University Hospital|