The Impact of Bariatric Surgery Induced Weight Loss on Lung Function in Adolescents
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|ClinicalTrials.gov Identifier: NCT02644174|
Recruitment Status : Recruiting
First Posted : December 31, 2015
Last Update Posted : April 13, 2017
|Condition or disease||Intervention/treatment|
|Obesity||Procedure: Bariatric Surgery|
Morbid obesity leads to restrictive as well as obstructive ventilatory defects via mechanisms that include mechanical, as well as inflammatory factors. We hypothesise that multiple breath nitrogen washout will be more sensitive to changes in small airway function than conventional lung function testing.
We will invite adolescents with morbid obesity, scheduled to undergo bariatric surgery at SCMCI during 2016-2018, for pulmonary function testing, including spirometry, plethysmography, nitrogen multiple breath washout, lung transfer factor and 6 minute walk. These tests will be conducted prior to the operation as well as during follow-up appointments at 3, 6 and 12 months. We will also evaluate oxidative stress using highly sensitive C-reactive protein as surrogate marker.
|Study Type :||Observational|
|Estimated Enrollment :||60 participants|
|Official Title:||The Impact of Bariatric Surgery Induced Weight Loss on Lung Function in Adolescents|
|Study Start Date :||May 2016|
|Estimated Primary Completion Date :||January 2019|
|Estimated Study Completion Date :||January 2020|
- Change from Baseline Lung Clearance Index [ Time Frame: 3 months post op ]
- Change from Baseline High sensitivity C reactive protein [ Time Frame: 3 months post op ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02644174
|Contact: Patrick Stafler, MDfirstname.lastname@example.org|
|Schneider Children's Medical Center of Israel||Recruiting|
|Petach Tikva, Israel, 49202|
|Contact: Patrick Stafler, MD 972547243623 email@example.com|