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Color and Pupil Function

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02636140
Recruitment Status : Completed
First Posted : December 21, 2015
Last Update Posted : November 2, 2016
Information provided by (Responsible Party):
Jamie M. Zeitzer, Ph.D., VA Palo Alto Health Care System

Brief Summary:
This study will examine the effects of different colors of light on pupil function and alertness.

Condition or disease Intervention/treatment Phase
Pupil Other: Light Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 10 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Basic Science
Official Title: Effect of Light Spectrum on Pupil Function
Study Start Date : February 2016
Actual Primary Completion Date : August 2016
Actual Study Completion Date : August 2016

Arm Intervention/treatment
Experimental: Light
Randomized amount and color of light
Other: Light
A brief, 1 minute exposure to light of varying color and intensity. The combination of color and intensity will be the same in all participants, but the order in which they are received is randomized.

Primary Outcome Measures :
  1. Change in pupil size [ Time Frame: Baseline and 10 minutes ]
    Change in pupil size from baseline during and following brief light exposure

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Aged 18-35
  • Good health

Exclusion Criteria:

  • Sleep disorder
  • Extreme chronotype
  • Smoker
  • Abnormal color vision
  • Ocular pathology (other than mild or moderate refractive error)
  • Visual field defects
  • Alcohol abuse
  • Use of illegal drugs
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Responsible Party: Jamie M. Zeitzer, Ph.D., Assistant Professor, VA Palo Alto Health Care System Identifier: NCT02636140    
Other Study ID Numbers: IRB-36326
First Posted: December 21, 2015    Key Record Dates
Last Update Posted: November 2, 2016
Last Verified: November 2016