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Trial record 8 of 163 for:    pituitary tumor

Follow-up Evaluation of Photo-Dynamic Therapy for Pituitary Tumours

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ClinicalTrials.gov Identifier: NCT02632084
Recruitment Status : Completed
First Posted : December 16, 2015
Last Update Posted : December 16, 2015
Sponsor:
Information provided by (Responsible Party):
The Leeds Teaching Hospitals NHS Trust

Brief Summary:
A study to followup patients that have previously been treated for pituitary tumours with either photodynamic therapy or placebo in a previous trial. The study aims to determine whether photodynamic therapy has any long term effect on tumour size, visual fields or endocrinological function.

Condition or disease
Pituitary Neoplasms

Detailed Description:
No patients will receive any medical or procedural treatments in this study, since these have been administered in a previous trial. The previous trial participants will be contacted and asked to attend a clinic or to have a telephone interview, where they will answer a questionnaire. They will be assessed clinically for visual fields, as well as undergoing an MRI scan of their head to assess tumour size (unless they have had a scan anyway in the previous 12 months), these tests would ordinarily form part of the routine outpatient workup for patients with pituitary tumours. There is no significant risk to the physical well-being of the patients with any of the methods to be used.

Study Type : Observational
Actual Enrollment : 30 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Follow-up Evaluation of Photo-Dynamic Therapy for Pituitary Tumours
Study Start Date : March 2010
Actual Primary Completion Date : September 2010
Actual Study Completion Date : September 2011

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. Tumour size on MRI scan. [ Time Frame: 6 months ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 100 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Details of previous research participants will be extracted from the study files by the researchers, who are all members of the direct care team.
Criteria

Inclusion Criteria:

  • Patients who were previously included in the initial pituitary PDT trial, in addition to those who were randomised as part of the RCT arm of the study. These patients have already participated in phase I/II trials. Of note, these patients all have pituitary tumours.

Exclusion Criteria:

  • Patients who were not included in the above mentioned trials. Patients included in the original trials who have subsequently died (of any cause).

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02632084


Locations
United Kingdom
Leeds Teaching Hospitals NHS Trust
Leeds, United Kingdom, LS1 3HE,
Sponsors and Collaborators
The Leeds Teaching Hospitals NHS Trust

Responsible Party: The Leeds Teaching Hospitals NHS Trust
ClinicalTrials.gov Identifier: NCT02632084     History of Changes
Other Study ID Numbers: NE13/10696
First Posted: December 16, 2015    Key Record Dates
Last Update Posted: December 16, 2015
Last Verified: December 2015

Additional relevant MeSH terms:
Pituitary Diseases
Pituitary Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Neoplasms
Hypothalamic Neoplasms
Supratentorial Neoplasms
Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms
Hypothalamic Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Endocrine System Diseases