Respiratory Mechanics Registry for ARDS Patients
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ClinicalTrials.gov Identifier: NCT02623192 |
Recruitment Status : Unknown
Verified July 2017 by Unity Health Toronto.
Recruitment status was: Recruiting
First Posted : December 7, 2015
Last Update Posted : July 26, 2017
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Condition or disease | Intervention/treatment |
---|---|
Acute Respiratory Distress Syndrome | Other: Patients who have performed the ARDS pulmonary function test |
Study Type : | Observational [Patient Registry] |
Estimated Enrollment : | 200 participants |
Observational Model: | Cohort |
Time Perspective: | Cross-Sectional |
Target Follow-Up Duration: | 3 Months |
Official Title: | Respiratory Mechanics in Acute Respiratory Distress Syndrome: A Quality Improvement-based Registry |
Study Start Date : | August 2014 |
Estimated Primary Completion Date : | August 2018 |
Estimated Study Completion Date : | August 2018 |

Group/Cohort | Intervention/treatment |
---|---|
ARDS |
Other: Patients who have performed the ARDS pulmonary function test |
- Driving pressure (centimetre of water) [ Time Frame: One hour ]Epidemiology of physiological abnormalities in respiratory mechanics were be reported.
- Transpulmonary pressure (centimetre of water) [ Time Frame: One hour ]
- Respiratory compliance (millilitre / centimetre of water) [ Time Frame: One hour ]
- Lung compliance (millilitre / centimetre of water) [ Time Frame: One hour ]

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Ages Eligible for Study: | Child, Adult, Older Adult |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- All patients admitted to the Medical-Surgical ICU, Trauma-Neuro ICU, and Cardiovascular ICU who meet the Berlin definition of ARDS and receive invasive ventilation.
Exclusion Criteria:
- Severe hemodynamic instability: > 30% variation of mean arterial pressure and/or heart rate (HR) in the last 2 hours or the need for a high dose of vasopressors (higher than 0.5 µg/kg/min of norepinephrine);
- Patients who present with a known esophageal problem, active upper gastrointestinal bleeding, or any other contraindication for the insertion of a gastric tube.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02623192
Contact: Laurent Brochard, MD | 416-864-5686 | BrochardL@smh.ca |
Canada, Ontario | |
St. Michael's Hospital | Recruiting |
Toronto, Ontario, Canada, M5B 1W8 | |
Contact: Laurent Brochard brochardl@smh.ca | |
Italy | |
Catholic University of the Sacred Heart | Recruiting |
Rome, Lazio, Italy, 00168 | |
Contact: Antonelli Massimo, MD +39 06 30153226 Massimo.Antonelli@unicatt.it |
Principal Investigator: | Laurent Brochard, MD | Unity Health Toronto |
Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Unity Health Toronto |
ClinicalTrials.gov Identifier: | NCT02623192 |
Other Study ID Numbers: |
REB# 15-098 |
First Posted: | December 7, 2015 Key Record Dates |
Last Update Posted: | July 26, 2017 |
Last Verified: | July 2017 |
Respiratory Distress Syndrome Respiratory Distress Syndrome, Newborn Acute Lung Injury Syndrome Disease Pathologic Processes |
Lung Diseases Respiratory Tract Diseases Respiration Disorders Infant, Premature, Diseases Infant, Newborn, Diseases Lung Injury |