Vibratory Stimuli, A Novel Rehabilitation Method for Preventing Post - Traumatic Knee Osteoarthritis
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|ClinicalTrials.gov Identifier: NCT02605876|
Recruitment Status : Recruiting
First Posted : November 16, 2015
Last Update Posted : October 11, 2018
|Condition or disease||Intervention/treatment||Phase|
|Knee Osteoarthritis||Device: Whole body vibration Device: Local muscle vibration||Not Applicable|
Quadriceps muscle dysfunction and proprioceptive deficits following knee injuries alter walking gait biomechanics in manners that contribute to development of knee osteoarthritis. Current rehabilitation techniques are minimally effective for addressing these complications and preventing knee osteoarthritis. Anterior cruciate ligament reconstruction dramatically increases the risk of knee osteoarthritis, and represents an ideal model for evaluating novel rehabilitation techniques for preventing knee osteoarthritis.
Direct (local muscle vibration) and indirect (whole body vibration) vibratory stimuli enhance quadriceps function and proprioception, and may improve rehabilitation and reduce the risk of knee osteoarthritis. The purpose of this investigation is to determine and compare the acute effects of whole body vibration and local muscle vibration on quadriceps function, knee proprioception, and gait biomechanics in individuals with anterior cruciate ligament reconstruction. The investigators hypothesize that vibratory stimuli will enhance quadriceps function, knee proprioception, and gait biomechanics in manners that would reduce the risk of developing knee osteoarthritis, and that whole body vibration and local muscle vibration will produce equivalent improvements in these characteristics.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||75 participants|
|Intervention Model:||Parallel Assignment|
|Primary Purpose:||Basic Science|
|Actual Study Start Date :||October 1, 2015|
|Estimated Primary Completion Date :||December 30, 2018|
|Estimated Study Completion Date :||September 30, 2019|
Experimental: Whole Body Vibration
Subjects will receive whole body vibration (30Hz, 2g) applied continuously for 1 minute. This exposure will be repeated 6 times with 2 minutes of rest between exposures.
Device: Whole body vibration
Experimental: Local Muscle Vibration
Subjects will receive local muscle vibration (30Hz, 2g) applied continuously for 1 minute. This exposure will be repeated 6 times with 2 minutes of rest between exposures.
Device: Local muscle vibration
No Intervention: Control
Subjects will perform the same procedures as the experimental groups with the exception that no vibratory stimulus will be applied.
- Change from baseline ground reaction force loading rate during walking gait immediately following vibration interventions [ Time Frame: Prior to and immediately following vibration interventions (i.e. acute effects) ]Ground reaction force loading rate during walking gait
- Change from baseline quadriceps strength immediately following vibration interventions assessed by peak torque during maximal quadriceps activation [ Time Frame: Prior to and immediately following vibration interventions (i.e. acute effects) ]Peak torque during maximal quadriceps activation
- Change from baseline knee proprioception immediately following vibration interventions assessed by joint reposition error [ Time Frame: Prior to and immediately following vibration interventions (i.e. acute effects) ]Joint reposition error
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02605876
|Contact: Troy Blackburn, PhDfirstname.lastname@example.org|
|Contact: Brian Pietrosimone, PhDemail@example.com|
|United States, North Carolina|
|Neuromuscular Research Lab, University of North Carolina at Chapel Hill||Recruiting|
|Chapel Hill, North Carolina, United States, 27599|
|Contact: Troy Blackburn, PhD 919-843-2021 firstname.lastname@example.org|
|Principal Investigator:||Troy Blackburn, PhD||University of North Carolina, Chapel Hill|