Intravenous Paracetamol Compared Dexketoprofen for Postoperative Analgesia After Septoplasty
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|ClinicalTrials.gov Identifier: NCT02602197|
Recruitment Status : Unknown
Verified November 2015 by Esra Caliskan, Baskent University.
Recruitment status was: Active, not recruiting
First Posted : November 11, 2015
Last Update Posted : November 11, 2015
Information provided by (Responsible Party):
Esra Caliskan, Baskent University
The investigators conducted a prospective, randomized, double blind study to compare the effectiveness of intravenous paracetamol and dexketoprofen for preventing pain during first 24 hours postoperative period in adult patient undergoing septoplasty.
|Condition or disease||Intervention/treatment||Phase|
|Postoperative Pain||Drug: Paracetamol Drug: Dexketoprofen||Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||2 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||The Efficacy of Intravenous Paracetamol Versus Dexketoprofen for Postoperative Pain Management After Septoplasty: A Prospective Randomized Double Blind Study|
|Study Start Date :||August 2013|
|Estimated Primary Completion Date :||December 2015|
|Estimated Study Completion Date :||February 2016|
Active Comparator: Paracetamol
1 gr paracetamol received intravenously bolus 15 minutes after anesthetic induction and at the postoperative 6 th,12 th, 18 th and 24 th hours
After anesthetic induction, the first I.V bolus injections of 1 gr paracetamol (total amount of 100 ml) were given during 15 minutes and then repeated every 6 h until 24 h postoperative period.
Other Name: Parol
Active Comparator: Dexketoprofen
50 mg dexketoprofen received intravenous bolus 15 minutes after anesthetic induction and at the postoperative 8 th,16 th and 24 th hours.
After anesthetic induction, the first I.V bolus injections of 50 mg Dexketoprofen (premixed with 0.9 % sodium chloride to total amount of 100 ml) were given during 15 minutes and then repeated every 8 h until 24 h postoperative period.
Other Name: Arveles
Primary Outcome Measures :
- Change from pain scores until postoperative 24 hours [ Time Frame: Pain scores recorded during postoperative 24 hours. ]Pain scores as measured by Visual Analog Scale (VAS) at 15 and 30 minutes, 1h, 2h, 4h, 6h, 12h, and 24 h after surgery
Secondary Outcome Measures :
- Cumulative tramadol consumption during postoperative 24 hours. [ Time Frame: First postoperative 24 hours ]Cumulative tramadol consumption was recorded during postoperative 24 hours.
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