Applied The Platelet Rich Fibrin in Chronic Periodontitis
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|ClinicalTrials.gov Identifier: NCT02594605|
Recruitment Status : Completed
First Posted : November 3, 2015
Last Update Posted : August 29, 2016
|Condition or disease||Intervention/treatment||Phase|
|Chronic Periodontitis||Device: Platelet Rich Fibrin Device: Conventional Flap Surgery||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||16 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Triple (Participant, Care Provider, Outcomes Assessor)|
|Official Title:||Investigation of the Contributions of Platelet Rich Fibrin Combined With Conventional Periodontal Flap on Periodontal Healing|
|Study Start Date :||December 2012|
|Actual Primary Completion Date :||June 2013|
|Actual Study Completion Date :||December 2013|
Experimental: Platelet Rich Fibrin
Platelet Rich Fibrin was applied with conventional flap surgery for treatment of periodontal bone loss in test group.
Device: Platelet Rich Fibrin
Platelet rich fibrin increases the growth factors. So it was applied for treatment of periodontal bone loss.
Active Comparator: Conventional Flap Surgery
Platelet Rich Fibrin was not applied to control groups. Only conventional flap surgery was applied to control groups.
Device: Conventional Flap Surgery
Only Conventional Flap Surgery treatment the bone loss limitedly.
- Levels of IGF-1, VEGF, BMP-2, FGF-2 on Weekly [ Time Frame: 4 weeks ]Change from baseline IGF-1, VEGF, BMP-2, FGF-2 levels of GCF at 1 month were measured by periopaper.
- Alteration of Clinical Attachment Level [ Time Frame: 6 month ]Change from baseline Clinical Attachment Levels at 6 months were measured with periodontal probe.
- Alteration of Periodontal Pocket Depth [ Time Frame: 6 month ]Change from baseline Pocket Depth at 6 months were measured with periodontal probe.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02594605
|Denizli, Turkey, 20010|
|Study Chair:||Yasin ÇiÇEK||Adıyaman University|