Impact of Particulate Matter on Mothers and Babies in Antwerp (IPANEMA) (IPANEMA)
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|ClinicalTrials.gov Identifier: NCT02592005|
Recruitment Status : Unknown
Verified November 2016 by Prof Yves Jacquemyn, Universiteit Antwerpen.
Recruitment status was: Recruiting
First Posted : October 30, 2015
Last Update Posted : December 1, 2016
Introduction: An emerging body of evidence indicates that there is an association between air pollution exposure in pregnancy and adverse pregnancy outcomes (Rudra, Williams, Sheppard , Koenig, & Schiff, 2011; Dadvand, et al., 2013; Ritz, et al., 2014). Adverse pregnancy outcomes tend to lead to adverse neonatal outcome and a higher economic cost. Epidemiologic studies have also revealed that cardiovascular complications during pregnancy, such als preeclampsia, are associated with a greater cardiovascular risk during later life ( Abramson & Melvin, 2014).
Aim: This study wants to examine the effects of exposure to environmental factors, polluents and particulate matter on the clinical pregnancy outcome for mother and child and to determine which biochemical changes in maternal, placental and cord blood best explain this effect.
Methods: This study will be performed in a prospective cohort setup (n=200), recruited from the prenatal clinic in the University Hospital Antwerp. The data collection consists of four questionnaires (intake, both urine samples and postpartum), two blood samples (28 weeks and post-partum), two urine samples (20 and 30 weeks), two hair samples (20 weeks and post-partum), cord blood and the placenta.
Results and conclusion: As the study will start in November 2014, no results are available yet.
|Condition or disease||Intervention/treatment|
|Pregnancy Preeclampsia||Other: amount of fine dust and other environmental exposure|
|Study Type :||Observational|
|Estimated Enrollment :||200 participants|
|Official Title:||Impact of Particulate Matter on Mothers and Babies in Antwerp (IPANEMA), a Prospective Cohort Study on the Impact of Pollutants and Particulate Matter in Pregnancy: Methodology and Design|
|Study Start Date :||May 2015|
|Estimated Primary Completion Date :||April 2017|
|Estimated Study Completion Date :||April 2018|
- Other: amount of fine dust and other environmental exposure
this study compares levels of exposure to to fine dust PM 2.5 by individual measurement both at home and at work
- preeclampsia [ Time Frame: From date of randomization until the date of delivery ]
- birth weight [ Time Frame: at delivery, assessed up to 40 weeks ]
- preterm birth [ Time Frame: at delivery, assessed up to 40 weeks ]
- gestational diabetes [ Time Frame: From date of randomization until the date of delivery ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02592005
|Contact: yves jacquemyn, PhDemail@example.com|
|Contact: Leen van den eeden, MDfirstname.lastname@example.org|
|Principal Investigator:||yves jacquemyn, PhD||Universiteit Antwerpen|