"Effect of Scaling and Root Planing on Liver Function Test (Alanine Aminotransferase and Aspartate Aminotransferase) in Systemically Healthy - Chronic Periodontitis Subjects: a Clinical Trial."
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|ClinicalTrials.gov Identifier: NCT02583841|
Recruitment Status : Completed
First Posted : October 22, 2015
Last Update Posted : October 22, 2015
To evaluate effect of non- surgical periodontal therapy on liver function in systemically healthy chronic periodontitis (CP) subjects.
Materials and methods:
The study is non surgical interventional trial, includes 50 CP subjects in the age group of 35- 60 years selected from the OPD (Out Patient Department) of department of periodontology Tatyasaheb Kore Dental College and Research center (TKDC and RC), Kolhapur. CP subjects were equally divided into test group and control group. Liver function test- aspartate aminotransferase (AST), alanine aminotransferase (ALT) were checked at baseline and at 1 month after treatment. Clinical examination includes plaque index, gingival index, sulcus bleeding index, probing depth, clinical attachment loss.
|Condition or disease||Intervention/treatment||Phase|
|Chronic Periodontitis (CP) Subjects.||Procedure: Scaling and root planing||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||50 participants|
|Intervention Model:||Parallel Assignment|
|Study Start Date :||February 2015|
|Actual Primary Completion Date :||March 2015|
|Actual Study Completion Date :||March 2015|
Active Comparator: Scaling and Root Planing( SRP)
This was an interventional study in which scaling and root planing was done in systemically healthy patients with chronic periodontitis
Procedure: Scaling and root planing
scaling and root planing as an intervention was done in patients of the test group
No Intervention: Control Group
Scaling and root planing was not done , that is no intervention is carried out in the patients of this group.
- Alanine aminotransferase [ Time Frame: 1month ]
- Aspartate aminotransferase [ Time Frame: 1 month ]
- plaque index [ Time Frame: 1month ]
- gingival index [ Time Frame: 1 month ]
- sulcus bleeding index [ Time Frame: 1month ]
- probing depth [ Time Frame: 1month ]
- Clinical attachment loss [ Time Frame: 1 month ]