Reconstitution of HIV-specific Immunity Against HIV
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02563509|
Recruitment Status : Recruiting
First Posted : September 30, 2015
Last Update Posted : May 23, 2017
|Condition or disease||Intervention/treatment||Phase|
|HIV||Biological: HIV-specific CD8 cells||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||40 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Reconstitution of HIV-specific Immunity Against HIV|
|Study Start Date :||January 2013|
|Estimated Primary Completion Date :||June 2017|
|Estimated Study Completion Date :||December 2017|
Experimental: HIV-specific CD8 cells
Transfusing HIV-specific CD8 cells 50-100mlonce a week for four times.
Biological: HIV-specific CD8 cells
Based on HAART, receive HIV-specific CD8 cells transfuion.
No Intervention: Regualar therapy
Only receiving Highly active anti-retroviral therapy(HAART).
- The number and function of HIV-specific CD8 cells in patients with HIV [ Time Frame: 6 Months ]The change of differentiation, proliferation, apoptosis, phenotype, etal.
- All adverse events [ Time Frame: 6 Months ]Chills, Fever, Headache, Nausea, Vomiting, Cough, Skin rashes, Anaphylactic shock, Etal.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02563509
|Contact: LingHua LI, email@example.com|
|Guangzhou 8th People's Hospital||Recruiting|
|Guangzhou, Guangdong, China, 510060|
|Contact: Linghua LI, doctor 13725297174 firstname.lastname@example.org|
|Principal Investigator:||Hui Zhang, doctor||Sun Yat-sen University|