Esmolol Versus Dexmedetomidine During Intracranial Procedures
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|ClinicalTrials.gov Identifier: NCT02563288|
Recruitment Status : Unknown
Verified July 2017 by Asouhidou Irene, George Papanicolaou Hospital.
Recruitment status was: Recruiting
First Posted : September 30, 2015
Last Update Posted : July 27, 2017
|Condition or disease||Intervention/treatment||Phase|
|Intracranial Aneurysm Intracranial Neoplasms||Drug: Esmolol Drug: Dexmedetomidine||Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||60 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Comparison of Esmolol and Dexmedetomidine on Sympathetic Control During Intracranial Procedures|
|Study Start Date :||August 2016|
|Estimated Primary Completion Date :||August 2017|
|Estimated Study Completion Date :||October 2017|
Active Comparator: Esmolol
Esmolol 500mcg/kg before induction in anesthesia following by 300mcg/Kg/min until extubation.
effect of esmolol on intraoperative sympathetic control and on extubation conditions.
Other Name: b adrenergic antagonist
Active Comparator: Dexmedetomidine
Dexmedetomidine 1mcg/Kg following by 0.7mcg/Kg/h until end of surgery.
effect of dexmedetomidine on intraoperative sympathetic control and on extubation conditions.
Other Name: alpha adrenergic agonist
- Systolic arterial pressure- mean arterial pressure (mmHg) [ Time Frame: every 15minutes, starting from the induction in anesthesia through surgery completion and up to first 24 postoperative hours. ]Status of patients during emerge from anaesthesia after intracranial surgery
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02563288
|Contact: Irene Asouhidou, MD, PhDemail@example.com|
|Contact: Dimitris Zosimidis, MDfirstname.lastname@example.org|
|George Papanikolaou General Hospital||Recruiting|
|Thessaloniki, Greece, 55133|
|Contact: Irene Asouhidou, MD, PhD 00302310452560 email@example.com|