Head and Neck Cancer in Children: A Retrospective Study
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|ClinicalTrials.gov Identifier: NCT02557048|
Recruitment Status : Not yet recruiting
First Posted : September 22, 2015
Last Update Posted : December 28, 2017
|Condition or disease|
|Head and Neck Neoplasms Cancer of Head and Neck Cancer of the Head and Neck Head and Neck Cancer Neoplasms, Head and Neck|
Although head and neck masses represent a common entity in children, malignancy is uncommon. Only very limited data are available in the literature on the incidence of childhood cancer of the head and neck worldwide.
Data from the United States National Cancer Institute database suggest that the head and neck are involved in 12 % of all childhood malignancies. The most common pediatric head and neck malignancies include Non Hodgkin lymphomas, Hodgkin lymphomas, rhabdomyosarcomas, thyroid malignancies, nasopharyngeal carcinomas (NPCs), salivary gland malignancies, and neuroblastomas.
Patients & Methods:
A hospital-based study, involving Pediatric cancer patients, those diagnosed with malignant tumors of the head & neck, in the period from 2001 January till 2015 December, and received treatment at the pediatric oncology department, their medical records will be retrospectively reviewed for data collection.
Clinico-laboratory data for each hisopathologic disease entity of various head & neck malignancies will be gathered. The demographic distribution for each disease entity in accordance with gender & age, and site preferences in these disease entities will be recorded. Treatment received & treatment outcomes will be verified and absolute frequencies & relative incidence of these disease entities will be calculated.
|Study Type :||Observational|
|Estimated Enrollment :||120 participants|
|Official Title:||Malignant Head and Neck Tumors in Children: A Retrospective Study|
|Estimated Study Start Date :||November 2018|
|Estimated Primary Completion Date :||January 2019|
|Estimated Study Completion Date :||February 2019|
- Overall survival (OS) [ Time Frame: Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years ]Time from the date of initiation of treatment until death from any cause
- Event Free Survival (EFS) [ Time Frame: Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years ]Time from the date of initiation of treatment until disease progression, or death for any reason.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02557048
|Assiut University||Not yet recruiting|
|Assiut, Egypt, 71515|
|Contact: Ahmed M. Morsy, MD +2 01003314522 email@example.com|
|Principal Investigator: Ahmed M. Morsy, MD|
|Principal Investigator: Badawy M. Ahmed, MD|
|Principal Investigator: Khalid M. Rezk, MD|
|Principal Investigator: Ameer M. Abuelgheet, MD|