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Trial record 28 of 288 for:    Lymphedema

Utility of MR Lymphangiography in Postoperative Follow-up of Lymphedema: Comparison With Lymphoscintigraphy

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ClinicalTrials.gov Identifier: NCT02550951
Recruitment Status : Unknown
Verified September 2015 by Seung Hong Choi, Seoul National University Hospital.
Recruitment status was:  Enrolling by invitation
First Posted : September 16, 2015
Last Update Posted : September 16, 2015
Sponsor:
Information provided by (Responsible Party):
Seung Hong Choi, Seoul National University Hospital

Brief Summary:
Its usefulness in implementing magnetic resonance angiography for postoperative follow-up of lymph lymphedema should try to evaluate and compare lymphoscintigraphy.

Condition or disease Intervention/treatment Phase
Lymphedema Procedure: lymphangiography Not Applicable

Detailed Description:

Surgical methods include " surgical procedure to make a good lymphatic drain 'and' surgical resection with lymph tissue swelling , significant that two of lymphedema .In recent years, began receiving the spotlight this former method using micro-surgery , inde essential that in order to increase the success rate of these micro-surgery accurately assess the structural abnormalities of preoperative lymphatic and establishing the surgical plan , the primary diagnostic imaging examination of existing lymphedema Since the nuclear medicine examination as to obtain an accurate anatomical information it is also ideal for imaging in the preoperative assessment of lymphedema is precisely that you can not .

In contrast magnetic resonance lymphangiography recently developed a new magnetic resonance imaging techniques that many advantages in precision assessment of lymphedema patients.

First, there are high spatial resolution magnetic resonance lymphangiography through the lymphatic vessels to obtain the correct anatomical information .

Second, magnetic resonance lymphangiography is provide not only information about the functional status of the lymphatic anatomical information .

Third, the magnetic resonance lymphangiography minimally invasive techniques , without exposure to radiation , is relatively easy and safe , that there is a great advantage of being able to diagnose the structural and functional at the same time or later in lymphatic vessels.

The magnetic resonance lymphangiography via the lymphatic advantage given also helps to establish a specific treatment plan , as well as accurate preoperative diagnosis of lymphedema that may contribute to enhance the success of micro-surgery.


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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 7 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Utility of Magnetic Resonance Lymphangiography in Postoperative Follow-up of Lymphedema: Comparison With Lymphoscintigraphy
Study Start Date : October 2014
Estimated Primary Completion Date : October 2016
Estimated Study Completion Date : October 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Lymphedema

Arm Intervention/treatment
Experimental: pre-operation Lymphedema
before magnetic resonance imaging(MRI), GADOVIST PFS [Bayer Korea] 7.5mL and local anesthetics 0.5m L mixed. and then 24 gauge needle using about 1 mL by the first , and second , the third the space between the toes intradermal injection , and then about 1-2 minutes , and massage the injection site, and Acquiring an image(coronal T1-weighted three-dimensional gradient-echo sequence) of the foot from a range including up to the pelvis from the comparison with lymphoscintigraphy
Procedure: lymphangiography
Experimental: post-operation Lymphedema
before magnetic resonance imaging(MRI), GADOVIST PFS [Bayer Korea] 7.5mL and local anesthetics 0.5m L mixed. and then 24 gauge needle using about 1 mL by the first , and second , the third the space between the toes intradermal injection , and then about 1-2 minutes , and massage the injection site, and Acquiring an image(coronal T1-weighted three-dimensional gradient-echo sequence) of the foot from a range including up to the pelvis from the comparison with lymphoscintigraphy
Procedure: lymphangiography



Primary Outcome Measures :
  1. pattern of lymph drainage (Scale of 0 to 5) [ Time Frame: After magnetic resonance lymphangiography scans in up to 2years ]
    0(abnormal)-10(normal)

  2. delay of lymph drainage (Scale of 0 to 10) [ Time Frame: After magnetic resonance lymphangiography scans in up to 2years ]
    0(delay)-10(normal)

  3. depiction of lymph vessels (Scale of 0 to 10) [ Time Frame: After magnetic resonance lymphangiography scans in up to 2years ]
    0(Not clarity)-10(Clarity)

  4. enhancement of inguinal lymph nodes (Scale of 0 to 10) [ Time Frame: After magnetic resonance lymphangiography scans in up to 2years ]
    0(Not clarity)-10(Clarity)

  5. Visibility of Lymphatic Duct (Scale of 0 to 10) [ Time Frame: After magnetic resonance lymphangiography scans in up to 2years ]
    0(Invisible)-10(Clearly visible)



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Ages Eligible for Study:   20 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • At least 20 years of age
  • Patients underwent preoperative and receive magnetic resonance lymphangiography and Lymphoscintigraphy At the postoperative 3 months

Exclusion Criteria:

  • Patients with a history of adverse effects on magnetic resonance contrast agents
  • Patients with a Decreased renal function(Glomerular filtration rate <30 mL / min)
  • Other, maternity, patients with a pacemaker or a cochlear

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02550951


Locations
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Korea, Republic of
Seoul National University Hospital
Seoul, Korea, Republic of, 110-744
Sponsors and Collaborators
Seoul National University Hospital
Investigators
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Principal Investigator: SeungHong Choi, MD,PhD Seoul National University Hospital(Radiology)

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Responsible Party: Seung Hong Choi, SeoulNUH, Seoul National University Hospital
ClinicalTrials.gov Identifier: NCT02550951     History of Changes
Other Study ID Numbers: D-1408-124-607
First Posted: September 16, 2015    Key Record Dates
Last Update Posted: September 16, 2015
Last Verified: September 2015

Additional relevant MeSH terms:
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Lymphedema
Lymphatic Diseases