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Impact of MELD Score for 700 Consecutive Liver Transplantations

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ClinicalTrials.gov Identifier: NCT02548130
Recruitment Status : Completed
First Posted : September 14, 2015
Last Update Posted : September 14, 2015
Sponsor:
Information provided by (Responsible Party):
Luc Massicotte, Centre hospitalier de l'Université de Montréal (CHUM)

Brief Summary:
The goal of this observational study was to evaluate the impact of the adoption of the MELD system to prioritize patients on the waiting list for OLT on survival for 700 consecutive liver transplantations. Survival was evaluated on the waiting list, one month, and one year after the transplantation. Another goal was to look at blood losses and transfusion requirement after the adoption of the MELD score. The hypothesis was the MELD system will ameliorate the survival rate on the waiting, but the post-OLT will be worse. Blood losses and transfusions could be worse with the MELD system.

Condition or disease Intervention/treatment
End Stage Liver Disease Other: MELD score

  Show Detailed Description

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Study Type : Observational
Actual Enrollment : 700 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Impact of the Introduction of the MELD Score to Prioritize the Waiting List on Survival, Blood Losses, And Transfusion Requirement for 700 Consecutive Liver Transplantations, Observational Study
Study Start Date : October 2002
Actual Primary Completion Date : October 2014
Actual Study Completion Date : October 2014

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
Patients before MELD score
Recipients before the MELD score
Patients after the MELD score
Recipients after the MELD score
Other: MELD score
introduction of MELD score




Primary Outcome Measures :
  1. Survival; [ Time Frame: one year ]

Secondary Outcome Measures :
  1. Bleeding [ Time Frame: Per-operatively ]
  2. transfusion of blood products [ Time Frame: Per0operatively ]


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Ages Eligible for Study:   17 Years to 70 Years   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
All patients for a liver transplantation
Criteria

Inclusion Criteria:

  • Patients for a liver transplantation at the investigators' institution

Exclusion Criteria:

  • None

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02548130


Sponsors and Collaborators
Centre hospitalier de l'Université de Montréal (CHUM)
Investigators
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Principal Investigator: Manon Choiniere, PhD CrCHUM

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Responsible Party: Luc Massicotte, Anesthesiologist, Centre hospitalier de l'Université de Montréal (CHUM)
ClinicalTrials.gov Identifier: NCT02548130     History of Changes
Other Study ID Numbers: Centre CHUM
First Posted: September 14, 2015    Key Record Dates
Last Update Posted: September 14, 2015
Last Verified: September 2015

Additional relevant MeSH terms:
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Liver Diseases
End Stage Liver Disease
Digestive System Diseases
Liver Failure
Hepatic Insufficiency