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Trial record 93 of 361 for:    "Speech Disorder"

An Evaluation of a New Nonverbal Treatment for Global Aphasia

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ClinicalTrials.gov Identifier: NCT02545894
Recruitment Status : Unknown
Verified September 2015 by University College, London.
Recruitment status was:  Recruiting
First Posted : September 10, 2015
Last Update Posted : September 10, 2015
Sponsor:
Information provided by (Responsible Party):
University College, London

Brief Summary:

People with global aphasia (PwGA) post stroke have little to no meaningful communication abilities (ie limited comprehension, spoken language, reading and writing abilities).A proportion of PwGA will also have limited abilities to use any alternative means of communication e.g. gesture, pictures or computer devices. There is a suggestion in the literature that this is because of co-occurring cognitive deficits. The consequence is that these clients are unable to reliably communicate even their basic needs.This is commonly known as having no functional communication abilities. Such PwGA tend not to respond to standard speech and language therapy interventions.

This research will investigate the effect of a new cognitive intervention designed to improve basic functional communication abilities. The treatment will be nonverbal and involve computer and paperbased tasks ordered hierarchically from basic to more complex tasks. Six to eight participants will take part. All their sessions will take place in their own home. For some this may be a care home. They will first complete a diagnostic communication assessment in order for baseline abilities to be established. Further formal language and cognitive assessments will be conducted over a period of 6 weeks. A relative/friend will complete a questionnaires about mood/communication. The PwGA will also be videoed interacting with the research student e.g. looking at a magazine, completing a jigsaw, answering questions and making choices non-verbally.

The participants then receive the new intervention 3 times a week for 6 consecutive weeks. All intervention sessions will be videoed. Then participants will be reassessed over 2 weeks using the same assessments as prior to the intervention. The questionnaire with their relative/friend and videoed activity session will also be repeated. After a twelve week break the participant will be videoed interacting with the research student complete some of the assessments again and their relative will re-complete the questionnaires.


Condition or disease Intervention/treatment Phase
Stroke Behavioral: Cognitive therapy Not Applicable

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 7 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: An Investigation Into the Effect of a Novel, Non Verbal, Cognitive Treatment on Functional Communication in Global Aphasia
Study Start Date : September 2014
Estimated Primary Completion Date : November 2015
Estimated Study Completion Date : September 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Aphasia

Arm Intervention/treatment
No Intervention: BASELINE TESTING
Language and cognitive assessments conducted
Experimental: Treatment

Intervention given:

visual tracking pressing a button every time a picture is seen on the screen

  • playing dominoes and snap
  • pressing a button every time a specific picture is seen on the screen
  • Pressing a button every time a specific sound is heard
  • Matching objects to a picture
  • Matching gestures to objects
  • Matching two connected objects
  • Sorting objects by categories
  • Matching sounds to objects
  • "Complete the category" and "odd on out with objects"
  • Choosing target objects by pointing
  • Choosing objects to complete the category by pointing
Behavioral: Cognitive therapy

The tasks are:

  • visually tracking a picture as it moves across the computer screen
  • pressing a button every time a picture is seen on the screen
  • pressing a button every time a specific picture is seen on the screen
  • Pressing a button every time a specific sound is heard
  • Matching objects to a picture
  • Matching gestures to objects
  • Matching two connected objects
  • Sorting objects by categories
  • Matching sounds to objects
  • "Complete the category" and "odd on out with objects"
  • Choosing target objects by pointing
  • Choosing objects to complete the category by pointing

No Intervention: Post intervention
Repeated testing



Primary Outcome Measures :
  1. American Speech and Hearing Association -Functional Assessment of Communication [ Time Frame: 27 weeks ]
    Questionnaire completed by friend/relative

  2. Constructed Interaction Task [ Time Frame: 27 weeks ]
    video recorded interaction


Secondary Outcome Measures :
  1. Aphasia Screening Test [ Time Frame: 14 weeks ]
    Language assessment

  2. Mood Screen [ Time Frame: 27 weeks ]
    depression screening tool

  3. Pyramids and Palm Trees Test [ Time Frame: 27 weeks ]
    pictorial semantic assessment

  4. Wisconsin Card Sorting Test [ Time Frame: 14 weeks ]
    cognitive assessment

  5. Butt Non verbal reasoning test [ Time Frame: 27 weeks ]
    cognitive assessment

  6. Western Aphasia Battery cognitive sub test [ Time Frame: 14 weeks ]
    cognitive assessment



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • have global aphasia as diagnosed by an SLT
  • have little or no verbal output
  • inconsistent single word comprehension
  • little or no ability to read or write
  • little or no ability to use alternative modes of communication
  • Little or no ability to make choices in function
  • no diagnosis/history of a progressive neurological condition
  • no diagnosis of hearing loss
  • no diagnosis/history of a mental health condition
  • English as a first language

Exclusion Criteria:

  • has another form of aphasia
  • is able to consistently express basic needs non-verbally or verbally.
  • is able to participate in communicative interaction with a familiar other
  • has a history of a progressive neurological condition
  • has hearing loss
  • has a diagnosis/history of a mental health condition
  • does not have English as a first language.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02545894


Contacts
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Contact: Sharon K Adjei, MRes 07984 186676 s.adjei12@ucl.ac.uk
Contact: Suzanne Beeke, PhD s.beeke@ucl.ac.uk

Locations
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United Kingdom
University College London, Research Dept of Language and Cognition Recruiting
London, United Kingdom, WC1N
Contact: Sharon K Adjei, MRes    +447984186676    s.adjei.12@ucl.ac.uk   
Contact: Suzanne Beeke, PhD       s.beeke@ucl.ac.uk   
Sponsors and Collaborators
University College, London
Investigators
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Principal Investigator: Suzanne Beeke, PhD UCL

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Responsible Party: University College, London
ClinicalTrials.gov Identifier: NCT02545894     History of Changes
Other Study ID Numbers: 13/0581
First Posted: September 10, 2015    Key Record Dates
Last Update Posted: September 10, 2015
Last Verified: September 2015

Additional relevant MeSH terms:
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Aphasia
Speech Disorders
Language Disorders
Communication Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms