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Exploratory Analysis on the Impact of Morbidities on Colorectal Cancer Screening Uptake

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ClinicalTrials.gov Identifier: NCT02503969
Recruitment Status : Completed
First Posted : July 21, 2015
Last Update Posted : December 2, 2015
Sponsor:
Information provided by (Responsible Party):
Ben Kearns, University of Sheffield

Brief Summary:

The primary aim of this project is to examine the association between having a long-term condition (morbidity) and screening uptake for colorectal cancer. Whilst this project will consider all morbidity and co-morbidities, there will be a particular focus on common mental health disorders, such as depression and anxiety.

The secondary aim of this project is to examine other factors that may influence uptake rate. Information on a wide array of potential factors is available for this project. These include demographics (age, gender, ethnicity), socio-economic status (deprivation, education status) and lifestyle (smoking status, drinking patterns, degree of exercise). In addition, any potential moderating effect of these factors on the association between morbidity and screening uptake shall be explored.

In summary, the following shall be explored:

  • Uptake rates by type of mental health disorder.
  • Uptake rates by chronic physical health problems.
  • Associations between uptake, morbidity (both physical and mental) and broader health determinants such as demographics, socio-economic status and lifestyle.

Condition or disease Intervention/treatment
Colorectal Cancer Other: Exposure to having a long-term condition.

  Show Detailed Description

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Study Type : Observational
Actual Enrollment : 8776 participants
Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Exploratory Analysis on the Impact of Morbidities on Colorectal Cancer Screening Uptake
Study Start Date : September 2015
Actual Primary Completion Date : December 2015
Actual Study Completion Date : December 2015

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
Screened
Those who received an adequate screen for colorectal cancer.
Other: Exposure to having a long-term condition.
Long-term conditions are self-reported: twelve named conditions are recorded, along with an "other" condition - these shall all be considered with the exception of the named condition "cancer".

Not Screened
Those who received an adequate screen for colorectal cancer.
Other: Exposure to having a long-term condition.
Long-term conditions are self-reported: twelve named conditions are recorded, along with an "other" condition - these shall all be considered with the exception of the named condition "cancer".




Primary Outcome Measures :
  1. Individual attended colorectal cancer screening [ Time Frame: The duration for which the individual was eligible for screening (between 1 and 10 years) ]
    If the individual attended any colorectal cancer screen (irrespective of the number of invitations) - analysed as a binary yes/no indicator per individual using logistic regression.


Secondary Outcome Measures :
  1. Individual accepted colorectal cancer screening after refusing the initial invitation for colorectal cancer screening [ Time Frame: The duration for which the individual was eligible for screening (between 1 and 10 years) ]
    This may not be assessed, depending on the available evidence. If analysed, will be as a binary yes/no indicator per individual using logistic regression.



Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years to 69 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
This study shall be restricted to participants in the South Yorkshire Cohort who have ticked both boxes on the Consent Form for their data to be used (the boxes being labelled "May we look at your health records?" and "May we use the information you provide to look at the benefit of health treatments?"), and are eligible for screening in the NHS Bowel Cancer Screening Programme (ages 60 to 69).
Criteria

Inclusion Criteria:

  • Participants in the South Yorkshire Cohort
  • Eligible for screening in the NHS Bowel Cancer Screening Programme.

Exclusion Criteria:

  • Have not ticked both boxes on the Consent Form (part of the South Yorkshire Cohort questionnaire) for their data to be used

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02503969


Locations
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United Kingdom
School of Health and Related Research
Sheffield, South Yorkshrie, United Kingdom, S11 8BA
Sponsors and Collaborators
University of Sheffield
Investigators
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Principal Investigator: Benjamin C Kearns, MSc University of Sheffield

Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: Ben Kearns, Research Associate, University of Sheffield
ClinicalTrials.gov Identifier: NCT02503969     History of Changes
Other Study ID Numbers: 15/YH/0028
First Posted: July 21, 2015    Key Record Dates
Last Update Posted: December 2, 2015
Last Verified: December 2015
Keywords provided by Ben Kearns, University of Sheffield:
Colorectal Cancer
Mass Screening
Uptake
Morbidity
Mental Health
Additional relevant MeSH terms:
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Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Neoplasms
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases