Functional Neural Connectivity at Rest as a Diagnostic Tool for Intolerance to Heat (fMRI)
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|ClinicalTrials.gov Identifier: NCT02498158|
Recruitment Status : Unknown
Verified July 2015 by Sheba Medical Center.
Recruitment status was: Not yet recruiting
First Posted : July 15, 2015
Last Update Posted : July 21, 2015
|Condition or disease||Intervention/treatment|
|Functional Neural Connectivity||Device: MRI scans|
20 healthy subjects that had already underwent Heat Tolerance Test (HTT) at the Heller Institute of Medical Research (Sheba Medical Center) will be recruited and divided into 2 groups: heat tolerant and heat intolerant (according to the HTT results). They will be asked to arrive to one experimental day at the imaging department in Sheba Medical Center and undergo anatomical and functional MRI scans.
Third group will consist of 10 existing brain scans (separated from personal details) of healthy males, at the same age range and who had never gone through heat injury.
Data will be analysed by fMRI expert in order to compare the functional neural connectivity at rest between the three groups.
|Study Type :||Observational|
|Estimated Enrollment :||20 participants|
|Official Title:||Functional Neural Connectivity at Rest, as a Diagnostic Tool for Intolerance to Heat and Return to Duty After Exertional Heat Stroke|
|Study Start Date :||September 2015|
|Estimated Primary Completion Date :||September 2016|
|Estimated Study Completion Date :||December 2016|
Functional neural connectivity at rest of 3 groups (heat tolerant, heat intolerant and healthy subjects) will be assessed using the anatomical and functional MRI scans and compared.
Device: MRI scans
20 subject (10 tolerant and 10 intolerant to heat) will undergo MRI scans (GE healthcare manufacturer) as follows:
scans of 10 healthy subjects will be taken from existing scans at the imaging department.
- functional neural connectivity [ Time Frame: one day ]MRI scans will be interpreted by fMRI expert and then compared between heat tolerant and intolerant subjects.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02498158
|Contact: Ofir Frenkel, M.D||+972529243399||Ofir.Frenkel@sheba.health.gov.il|
|Sheba medical center|
|Tel-Hashomer, Ramat- Gan, Israel|
|Principal Investigator:||Ofir Frenkel, M.D||Sheba Medical Center|