The Effect of Terlipressin in the Prevention of Type 2 Hepatorenal Syndrome by Improving Mean Arterial Pressure
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|ClinicalTrials.gov Identifier: NCT02489864|
Recruitment Status : Unknown
Verified July 2015 by Chan Xie, Sun Yat-sen University.
Recruitment status was: Recruiting
First Posted : July 3, 2015
Last Update Posted : July 3, 2015
|Condition or disease||Intervention/treatment||Phase|
|Hepatorenal Syndrome||Drug: Terlipressin||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||30 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Study Start Date :||July 2015|
|Estimated Primary Completion Date :||July 2017|
|Estimated Study Completion Date :||December 2017|
Active Comparator: Terlipressin and albumin
Patients in this group received terlipressin as an intravenous bolus of 0.5 mg every 6 h. If a significant reduction in serum creatinine level (≥1 mg/dL) was not observed during 3-day period, the dose of terlipressin was increased in a stepwise fashion every 3 days to a maximum of 2 mg every 6 hour.
albumin (Albumin 20 percent; Instituto Grífols, Barcelona, Spain) was given at a dose of 10 gram per day.
Placebo Comparator: Albumin
Only albumin (Albumin 20 percent; Instituto Grífols, Barcelona, Spain) was given at a dose of 10 gram per day.
- HRS incidence rate [ Time Frame: one year ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02489864
|Contact: Chan Xie, Dr.||firstname.lastname@example.org|
|The Third Affiliated Hospital of Sun Yat-Sen University||Recruiting|
|Guangzhou, Guangdong, China, 510630|
|Contact: Chan Xie, Dr. 8602085252372 email@example.com|