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Food Choices in Healthy Weight Women

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT02481362
First Posted: June 25, 2015
Last Update Posted: July 17, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Hollie Raynor, University of Tennessee
  Purpose
This study will examine differences in habituation to foods high in sugar and fat content versus those that are not, in normal weight women.

Condition Intervention
Addictive Behavior Food Preferences Food Habits Healthy Habituation Other: CAKE Other: APRICOTS

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Participant)
Primary Purpose: Basic Science
Official Title: Food Choices in Healthy Weight Women

Further study details as provided by Hollie Raynor, University of Tennessee:

Primary Outcome Measures:
  • Grams of consumption of cake [ Time Frame: 60 minutes ]
    Amount of cake consumed will be measured using the following formula: amount of cake before consumption (first weight) - amount of cake following consumption (second weight).

  • Grams of consumption of apricots [ Time Frame: 60 minutes ]
    Amount of apricots consumed will be measured using the following formula: amount of apricots before consumption (first weight) - amount of apricots following consumption (second weight).


Enrollment: 28
Study Start Date: June 2015
Study Completion Date: May 2016
Primary Completion Date: May 2016 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Order 1
Order for sessions: Cake, apricots
Other: CAKE
For the CAKE condition, participants will play a computer task to earn points for cake that they can consume.
Other: APRICOTS
For the APRICOTS condition, participants will play a computer task to earn points for apricots that they can consume.
Active Comparator: Order 2
Order for sessions: apricots, Cake
Other: CAKE
For the CAKE condition, participants will play a computer task to earn points for cake that they can consume.
Other: APRICOTS
For the APRICOTS condition, participants will play a computer task to earn points for apricots that they can consume.

Detailed Description:

Participants will complete two experimental sessions, in which habituation to chocolate cake and dried apricots will be measured, with each session measuring habituation rate to one food. Upon arrival to the session, participants will write down what they have consumed and the minutes of physical activity they have engaged in during the previous 24 hours. Participants will rate their feelings of hunger and fullness using a 100mm VAS. They will also rank their liking of the food being used in the session using a 100mm VAS. Participants will be given a peanut butter flavored granola bar, containing 190 kcal, and be instructed to consume all of the bar.

Next, participants will complete a computer generated task to measure habituation to a food (chocolate cake or apricots). The computer task will be programmed at a variable interval of 120 ± 42 seconds (VI-120) reinforcement schedule, so that participants will be rewarded one point for the first response made after approximately 120s have passed. The computer task consists of two squares, one that flashes red every time a mouse button is pressed and another square that flashes green when a point is earned. The habituation phase will be 24 minutes, divided into 12, 2-minute trials, during which participants can earn points towards access to 75 kcal portions of the food that is being measured. Participants will receive the food immediately after each point is earned to consume and can continue to play the computer task while eating. Participants will be instructed that when they no longer want to earn access to the food they can go to another table and engage in the activities provided (i.e., reading magazines). After the computer task, participants will rate their feeling of hunger, fullness, and liking of the food. During the computer task the number of consecutive two-minute time blocks before responding ceases, as well as the overall pattern of responding, will be measured.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • body mass index (BMI) 18.5 to 24.9 kg/m2
  • nonsmokers
  • not allergic to the foods used in the investigation
  • must like the foods in the investigation (scoring > 50 mm on a visual analogue scale [VAS])
  • be willing to consume the foods
  • not have dietary restrictions
  • not be a restrained eater (scoring > 12 on the Three Factor Eating Scale)
  • not be on medications that influence appetite
  • not planning to change their diet or physical activity during the time frame of their study participation
  • not dieting or trying to lose weight.

Exclusion Criteria:

  • BMI outside of the range 18.5-24.9
  • smoker
  • food allergies
  • does not like the foods used in the study
  • has dietary restrictions
  • is a restrained eater
  • on medications that may influence appetite
  • planning on changing diet or physical activity during time frame of the study
  • dieting
  • trying to lose weight
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02481362


Locations
United States, Tennessee
Healthy Eating and Activity Laboratory, University of Tennessee
Knoxville, Tennessee, United States, 37996
Sponsors and Collaborators
University of Tennessee
Investigators
Principal Investigator: Hollie Raynor, PhD University of Tennessee, Knoxville
  More Information

Publications:

Responsible Party: Hollie Raynor, PhD, RD, LDN, University of Tennessee
ClinicalTrials.gov Identifier: NCT02481362     History of Changes
Other Study ID Numbers: UTK IRB-15-02330-XP
First Submitted: June 23, 2015
First Posted: June 25, 2015
Last Update Posted: July 17, 2017
Last Verified: July 2017

Additional relevant MeSH terms:
Behavior, Addictive
Compulsive Behavior
Impulsive Behavior