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Evaluation of Meibomian Gland Dysfunction in Chinese Old Patients

This study is currently recruiting participants.
Verified June 2015 by yin ying zhao, Wenzhou Medical University
Sponsor:
ClinicalTrials.gov Identifier:
NCT02481167
First Posted: June 25, 2015
Last Update Posted: June 25, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
yin ying zhao, Wenzhou Medical University
  Purpose
The purpose of this study is to identify age-related changes in chinese meibomian glands that may be associated with meibomian gland dysfunction (MGD).

Condition
Dry Eye

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional

Resource links provided by NLM:


Further study details as provided by yin ying zhao, Wenzhou Medical University:

Primary Outcome Measures:
  • Tear film break-up time [ Time Frame: 1 year ]
    Tear film break-up time (TBUT) was evaluated by placing a single fluorescein strip over the inferior tear meniscus after instilling a drop of normal saline.

  • Lower tear meniscus [ Time Frame: 1 year ]
    Lower tear meniscus was evaluated by keratography

  • The morphology of meibomian glands [ Time Frame: 1 year ]
    The morphology of meibomian glands was evaluated by keratography


Estimated Enrollment: 100
Study Start Date: January 2015
Estimated Study Completion Date: January 2018
Estimated Primary Completion Date: April 2016 (Final data collection date for primary outcome measure)
Groups/Cohorts
group1
This study was consisted of patients with older than 40 years of age who complained with dry eye.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   40 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
This study was consisted of patients with older than 40 years of age who complained with dry eye. The institutional review board of Wenzhou Medical College approved the study protocol, and all patients provided their informed consent.
Criteria

Inclusion Criteria:

  • have dry eye symptom
  • have meibomian gland dysfunction

Exclusion Criteria:

  • diabetes
  • history of ocular surgery
  • systemic disease or inflammation
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02481167


Contacts
Contact: yinying zhao, PhD 86-057788068859 ginger146@126.com

Locations
China, Zhejiang
Wenzhou Medical University Recruiting
Wenzhou, Zhejiang, China, 325027
Contact: XIXIA DING, PHD    86-057788068859      
Sponsors and Collaborators
Wenzhou Medical University
Investigators
Study Chair: ZHAO YUNE, MS Wenzhou Medical University
  More Information

Responsible Party: yin ying zhao, Wenzhou Medical University
ClinicalTrials.gov Identifier: NCT02481167     History of Changes
Other Study ID Numbers: WZ-ZYY-DRYEYE
First Submitted: June 15, 2015
First Posted: June 25, 2015
Last Update Posted: June 25, 2015
Last Verified: June 2015

Keywords provided by yin ying zhao, Wenzhou Medical University:
Aged
Meibomian Glands
dry eye
Elderly