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Evaluation of Meibomian Gland Dysfunction in Chinese Old Patients

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ClinicalTrials.gov Identifier: NCT02481167
Recruitment Status : Unknown
Verified June 2015 by yin ying zhao, Wenzhou Medical University.
Recruitment status was:  Recruiting
First Posted : June 25, 2015
Last Update Posted : June 25, 2015
Sponsor:
Information provided by (Responsible Party):
yin ying zhao, Wenzhou Medical University

Brief Summary:
The purpose of this study is to identify age-related changes in chinese meibomian glands that may be associated with meibomian gland dysfunction (MGD).

Condition or disease
Dry Eye

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Cross-Sectional
Study Start Date : January 2015
Estimated Primary Completion Date : April 2016
Estimated Study Completion Date : January 2018

Group/Cohort
group1
This study was consisted of patients with older than 40 years of age who complained with dry eye.



Primary Outcome Measures :
  1. Tear film break-up time [ Time Frame: 1 year ]
    Tear film break-up time (TBUT) was evaluated by placing a single fluorescein strip over the inferior tear meniscus after instilling a drop of normal saline.

  2. Lower tear meniscus [ Time Frame: 1 year ]
    Lower tear meniscus was evaluated by keratography

  3. The morphology of meibomian glands [ Time Frame: 1 year ]
    The morphology of meibomian glands was evaluated by keratography



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Ages Eligible for Study:   40 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
This study was consisted of patients with older than 40 years of age who complained with dry eye. The institutional review board of Wenzhou Medical College approved the study protocol, and all patients provided their informed consent.
Criteria

Inclusion Criteria:

  • have dry eye symptom
  • have meibomian gland dysfunction

Exclusion Criteria:

  • diabetes
  • history of ocular surgery
  • systemic disease or inflammation

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02481167


Contacts
Contact: yinying zhao, PhD 86-057788068859 ginger146@126.com

Locations
China, Zhejiang
Wenzhou Medical University Recruiting
Wenzhou, Zhejiang, China, 325027
Contact: XIXIA DING, PHD    86-057788068859      
Sponsors and Collaborators
Wenzhou Medical University
Investigators
Study Chair: ZHAO YUNE, MS Wenzhou Medical University

Responsible Party: yin ying zhao, Wenzhou Medical University
ClinicalTrials.gov Identifier: NCT02481167     History of Changes
Other Study ID Numbers: WZ-ZYY-DRYEYE
First Posted: June 25, 2015    Key Record Dates
Last Update Posted: June 25, 2015
Last Verified: June 2015

Keywords provided by yin ying zhao, Wenzhou Medical University:
Aged
Meibomian Glands
dry eye
Elderly