Survey on the Treatment Reality of Patients With Epidermal Growth Factor Receptor (EGFR) Mutation-positive Non-small Cell Lung Cancer(NSCLC)
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According to the recent report using EGFR tyrosine kinase inhibitors (EGFR-TKI), there is all over survival of the EGFR gene mutation-positive NSCLC in a tendency to extension. However, the real situation and the reason are not clarified.This observational study collects the data of EGFR gene mutation-positive NSCLC approximately 2,000 from the medical record of approximately 20 facilities in Japan and observes the treatment reality of EGFR gene mutation-positive NSCLC.
Overall survival of the patients. [ Time Frame: Up to 3 monthes. Data will be collected retrospectively from medical records.Survival status as of the end of December 2014, date of death or date of last follow-up of survival. ]
Secondary Outcome Measures :
Overall survival by patient background [ Time Frame: Up to 3 monthes. Data will be collected retrospectively from medical records. ]
Overall survival by treatment sequence [ Time Frame: Up to 3 monthes. Data will be collected retrospectively from medical records. ]
Treatment time by treatment category [ Time Frame: Up to 3 monthes. Data will be collected retrospectively from medical records. ]
Time to Treatment Failure (TTF) of Gefitinib treatment [ Time Frame: Up to 3 monthes. Data will be collected retrospectively from medical records. ]
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Ages Eligible for Study:
Child, Adult, Older Adult
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Approximately 2000, Advanced Non Small Cell Lung cancer (aNSCLC) patients who fulfil the inclusion/exclusion criteria will be recruited by 10 to 20 investigational sites in Japan.
1. EGFR mutation-positive progress recurrent non-small cell lung cancer subject.
2. Subjects who commenced on first-line treatment between January, 2008 and December 2012.
1. Patients has a treatment history with the drug which was not approved for marketing authorization as of 31th December , 2014
2. Person who were planning and/or getting involved in this survey. (applies to both AstraZeneca staff and/or staff at the study site)
3. Previous enrolment in the present study.
4. Patient was not evaluated to be appropriate for study enrolment by the investigators