Dicrotic Notch and Hypotension at Caesarean Under Spinal Anaesthesia (DINOCS)
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|ClinicalTrials.gov Identifier: NCT02437799|
Recruitment Status : Completed
First Posted : May 8, 2015
Last Update Posted : October 13, 2016
Hypotension occurs commonly during spinal anaesthesia for caesarean section and may result in detrimental effects to the mother and foetus. A previous pilot study where images of the pulse oximeter waveform study were taken, found that the dicrotic wave moved away from the systolic wave during the onset of hypotension.
The investigators wish to download electronic data which describe the pulse oximeter pulse wave to more accurately assess movement of the diastolic wave relative to the systolic wave during spinal anaesthesia for caesarean section.
20 women undergoing caesarean section under spinal anaesthesia will be recruited by informed consent for this observational study. Data downloaded from the pulse oximeter will be analysed to identify movement of the dicrotic wave relative to the systolic wave and this will be related to changes in blood pressure.
The investigators will establish best way to analyse changes in the pulse oximeter waveform and the relationship between changes in pulse oximeter waveform morphology and the onset of hypotension during spinal anaesthesia for caesarean section.
Analysis of movement of the dicrotic wave could be used to anticipate and thus avoid severe hypotension during spinal anaesthesia for caesarean section.
|Condition or disease||Intervention/treatment|
|Hypotension||Other: Dicrotic wave analysis|
Show Detailed Description
|Study Type :||Observational|
|Actual Enrollment :||20 participants|
|Official Title:||Analysis of Changes in the Pulse Oximeter Waveform and Blood Pressure During Spinal Anaesthesia for Caesarean Section: an Observational Study|
|Study Start Date :||September 2015|
|Actual Primary Completion Date :||December 2015|
|Actual Study Completion Date :||December 2015|
Caesarean section spinal anaesthesia
Dicrotic Wave analysis of pulse oximeter of Women undergoing planned caesarean section under spinal anaesthesia.
Other: Dicrotic wave analysis
We will download data from the pulse oximeter that is being used to monitor the patient during their surgery.
- 1. To download electronic data which describe the pulse oximeter pulse wave to accurately assess movement of the diastolic wave relative to the systolic wave during spinal anaesthesia for caesarean section. [ Time Frame: Data will be downloaded for approximately 20 minutes ]Data will be collected during planned caesarean section under spinal anaesthesia
- Time course of cardiovascular changes [ Time Frame: twenty minutes ]1. To clearly document the time-course of cardiovascular changes and hypotension during spinal for caesarean section
- Preliminary cardiovascular data [ Time Frame: twenty minutes ]2. To provide preliminary data to characterise cardiovascular changes during hypotension
- Vascular behaviour [ Time Frame: twenty minutes ]4. To characterise changes in vascular behaviour, and to determine their time course, before and after onset of hypotension and the given treatment.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02437799
|Sheffield NHS Trust|
|Sheffield, South Yorkshire, United Kingdom, S10 2JF|
|Principal Investigator:||ian Wrench, MBChB,FRCA||Sheffield Teaching Hospitals NHS Foundation Trust|