Anesthetic Management in Fetoscopic Surgery and Incidence of Complications
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|ClinicalTrials.gov Identifier: NCT02434926|
Recruitment Status : Completed
First Posted : May 6, 2015
Last Update Posted : August 12, 2016
Fetoscopic surgery has been acknowledged to be a reliable procedure to correct several congenital anomalies e.g. shunt insertion in fetal bladder outlet obstruction, laser ablation of vessels in twin-twin transfusion syndrome (TTTS), balloon occlusion in congenital diaphragmatic hernia etc. The technique involves an introduction of small-caliber instruments into the amniotic cavity under ultrasound guidance. This procedure can be successfully done under either general anesthesia, regional anesthesia or local anesthesia with sedation. Each technique has both advantages and drawbacks.
Several complications related to anesthetic after fetoscopic surgery can occur. For instance, pulmonary edema which is caused by intravenous fluid loading, irrigation fluid absorption or fluid flow through myometrium venous channel. Besides, maternal hypotension intraoperatively can arise from spinal anesthesia.
The aim of the study is to report choice of anesthesia using in fetoscopic surgery in the tertiary care institute (Siriraj hospital) and incidence of complications which may relate to different anesthetic techniques.
|Condition or disease|
|Fetoscopy Anesthetic Complications Pregnancy|
The quantity and types of medications using in different anesthetic technique will be gathered including opioid, benzodiazepine, propofol, detail of drugs making fetal paralysis, amount of local anesthetic drug in spinal anesthesia etc. Tocolytic drug will also be recorded eg. terbutaline, nifedipine or magnesium sulfate. These drugs have been generally known that may cause hypotension or pulmonary edema.
In intraoperative period, the investigators emphasize in the incidence of hypotension and other possible complications such as pulmonary aspiration, failed intubation, maternal desaturation or maternal bradycardia. Volume of intravenous fluid administered and amount of irrigation fluid will also be recorded.
Maternal and fetal outcome in recovery room and in postoperative period will be collected.
|Study Type :||Observational|
|Actual Enrollment :||152 participants|
|Official Title:||Anesthetic Management in Fetoscopic Surgery and Incidence of Complications - A Retrospective Review|
|Study Start Date :||May 2015|
|Actual Primary Completion Date :||January 2016|
|Actual Study Completion Date :||February 2016|
- Type of anesthetic techniques used in fetoscopic surgery [ Time Frame: in operating theatre ]Type of anesthetic techniques eg. general anesthesia, regional anesthesia, local anesthesia with sedation.
- Types and quantity of anesthetic medications used [ Time Frame: in operating theatre ]Types and quantity of anesthetic medications used for anesthetize patients in different anesthetic techniques.
- Incidence of complications [ Time Frame: in operating theatre ]Intraoperative complications eg. failed intubation, aspiration, hypotension from spinal anesthesia, high spinal block, desaturation etc.
- Incidence of complications [ Time Frame: after surgery till patients discharge from the hospital ]Complications occurring postoperatively include pulmonary edema, fatal death etc.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02434926
|Anesthesiology department, Siriraj hospital, Mahidol University|
|Bangkok, Thailand, 10700|
|Siriraj Hospital, Mahidol University|
|Bangkok, Thailand, 10700|
|Principal Investigator:||Patchareya Nivatpumin, M.D.||Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand|