Effects of Chest Physiotherapy (CPT) on Lung Clearance Index (LCI) in Non Cystic Fibrosis (CF) Bronchiectasis
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|ClinicalTrials.gov Identifier: NCT02411981|
Recruitment Status : Completed
First Posted : April 8, 2015
Last Update Posted : March 22, 2016
|Condition or disease||Intervention/treatment||Phase|
|Bronchiectasis||Other: Autogenic drainage||Not Applicable|
This is a before-after intervention study.
Spirometry, body plethysmography and then multiple breath nitrogen washout will be measured before the application of chest physiotherapy.
The chest physiotherapy technique used will be autogenic drainage during 30 minutes. A resting period of 5 minutes will be given to the participant before the following tests.
Spirometry, body plethysmography and then multiple breath nitrogen washout will be measured again, in the same order, after the application of chest physiotherapy.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||24 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Short-term Effects of Chest Physiotherapy on Ventilation Inhomogeneity in Non-CF Bronchiectasis|
|Study Start Date :||April 2015|
|Actual Primary Completion Date :||October 2015|
|Actual Study Completion Date :||February 2016|
The autogenic drainage will be the chest physiotherapy technique used for this study.
Autogenic drainage is an airway clearance technique that attempts to obtain the optimal airflow to evacuate the secretions. This technique uses modulation of inspiratory and expiratory airflow at different breathing level within the vital capacity.
Other: Autogenic drainage
- Change of Lung Clearance Index (LCI) [ Time Frame: up to 80 minutes ]LCI will me measured before and after the chest physiotherapy session
- Change of Spirometry [ Time Frame: up to 40 minutes ]Forced expired volume in one second (FEV1) and Forced expired flow at 25-75% of the forced vital capacity (FEF25-75) will be measured before and after the chest physiotherapy session
- Sputum weight [ Time Frame: 35 minutes ]Sputum will be collected during the 30 minutes of chest physiotherapy session and 5 minutes immediately after. Sputum weight will be measured and correlated with change of LCI and spirometry values
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02411981
|Cliniques universitaires Saint-Luc|
|Brussels, Belgium, 1200|
|Study Director:||Sophie Gohy, MD, PhD||Cliniques universitaires Saint-Luc- Université Catholique de Louvain|
|Principal Investigator:||William Poncin, PhD student||Cliniques universitaires Saint-Luc- Université Catholique de Louvain|
|Study Chair:||Grégory Reychler, PhD||Cliniques universitaires Saint-Luc- Université Catholique de Louvain|