Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study (ARTEMIS)
|ClinicalTrials.gov Identifier: NCT02406677|
Recruitment Status : Completed
First Posted : April 2, 2015
Last Update Posted : October 23, 2017
|Condition or disease||Intervention/treatment||Phase|
|Cost Sharing, Acute Coronary Syndrome||Other: Study voucher card||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||11001 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Health Services Research|
|Official Title:||Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study|
|Actual Study Start Date :||June 5, 2015|
|Actual Primary Completion Date :||October 1, 2017|
|Actual Study Completion Date :||October 1, 2017|
Experimental: Copayment Intervention Arm
Sites in the intervention arm will provide patients with a study voucher card to offset any patient copayments or medication card for the filling of any prescriptions of clopidogrel or ticagrelor.
Other: Study voucher card
Study voucher card to offset any patient copayments or medication costs for the filling of any prescriptions of clopidogrel or ticagrelor
No Intervention: Usual Care Arm
For hospitals randomized to the control arm, all patients receive usual care and no study intervention is performed.
- Major Adverse Cardiovascular Events [ Time Frame: 12 months ]To determine if patient copayment reduction leads to lower risk of MACE (composite of death, MI, and stroke) at 1 year after discharge.
- Long Term Persistence to P2Y12 receptor inhibitor [ Time Frame: 12 months ]To determine if patient copayment reduction leads to higher long-term persistence of any P2Y12 receptor inhibitor at 1 year after discharge.
- P2Y12 receptor inhibitor selection [ Time Frame: 12 months ]To evaluate whether reducing patient copayments for both generic and brand P2Y12 receptor inhibitor options affects medication selection at discharge.
- Healthcare Resource Utilization [ Time Frame: 12 months ]To assess the impact of copayment reduction on the total cost of health care for patients after myocardial infarction.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02406677
Show 272 Study Locations
|Principal Investigator:||Tracy Wang, MD, MHS, MSc||Duke University|
|Study Chair:||Eric Peterson, MD, MPH, FAHA, FACC||Duke University|