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Trial record 5 of 611 for:    Personality Disorders

Mindfulness and Interpersonal Effectiveness Skills in Borderline Personality Disorder

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ClinicalTrials.gov Identifier: NCT02397031
Recruitment Status : Completed
First Posted : March 24, 2015
Last Update Posted : March 25, 2015
Sponsor:
Information provided by (Responsible Party):
Juan Carlos Pascual, Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Brief Summary:
The purpose of the study was to determine whether mindfulness training could be more effective than another active intervention in reducing borderline personality disorder (BPD) symptoms. The main hypothesis was that patients allocated to the mindfulness group would show a greater improvement on global BPD symptomatology. As a second objective, we explored some of the possible underlying mechanisms of both active treatments. For that purpose, changes in decentering, mindfulness facets and cognitive processing of social interactions were also evaluated.

Condition or disease Intervention/treatment Phase
Borderline Personality Disorder Behavioral: Mindfulness Behavioral: interpersonal effectiveness Not Applicable

Detailed Description:
The present study aimed at evaluating the efficacy of mindfulness skills (M) versus interpersonal effectiveness skills (IE) on borderline symptoms. For that purpose, a randomized, active-controlled clinical trial was designed. 64 participants with borderline personality disorder (BPD) diagnosis were allocated to mindfulness (n=32) or interpersonal effectiveness skills (n=32). Both interventions were delivered over a 10-week period. The borderline symptom list (BSL-23) was elected as the primary outcome measure. Mindfulness related capacities, decentering and cognitive processing of social interactions were also evaluated with the Five Facet Mindfulness Questionnaire (FFMQ), the Experiences Questionnaire (EQ) and the Multidimensional Scale of Social Expression (EMES-C), respectively. Assessments were conducted pre and post interventions.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 64 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
Official Title: Randomized, Active-controlled, Clinical Trial Comparing Effects of Mindfulness and Interpersonal Effectiveness Skills in Borderline Personality Disorder
Study Start Date : September 2011
Actual Primary Completion Date : April 2014
Actual Study Completion Date : April 2014

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Mindfulness
As proposed in dialectical behavioral therapy, mindfulness training consist of a set of behavioral skills that aim at improving patient`s attentional control and emotional regulation.
Behavioral: Mindfulness
weekly psychotherapy sessions for 10 weeks (120 min each)

Active Comparator: Interpersonal effectiveness
Interpersonal effectiveness skills are focused on improving interpersonal relationships and enhancing patient`s ability to display social effective behavior.
Behavioral: interpersonal effectiveness
weekly psychotherapy sessions for 10 weeks (120 min each)




Primary Outcome Measures :
  1. change from baseline in borderline symptoms after a 10 week intervention [ Time Frame: 10 weeks ]
    participants were assessed pre and post interventions


Secondary Outcome Measures :
  1. change from baseline in decentering after a 10 week intervention [ Time Frame: 10 weeks ]
    participants were assessed pre and post interventions

  2. change from baseline in mindfulness facets after a 10 week intervention [ Time Frame: 10 weeks ]
    participants were assessed pre and post interventions

  3. change from baseline in social interactions after a 10 week intervention [ Time Frame: 10 weeks ]
    participants were assessed pre and post interventions



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion criteria:

  • Ages between 18 and 45 years
  • BPD criteria according to two diagnostic interviews (SCID-II and DIB-R)

Exclusion Criteria:

  • Lifetime diagnosis of schizophrenia, drug-induced psychosis, organic brain syndrome, bipolar disorder or mental retardation
  • Participating in any sort of psychotherapy during the study or having participated in dialectical behavioral therapy groups in the past

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02397031


Sponsors and Collaborators
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Investigators
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Principal Investigator: Juan C Pascual, PhD Servei de Psiquitria. Hospital de la Santa Creu i Sant Pau

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: Juan Carlos Pascual, Psychiatrist, Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
ClinicalTrials.gov Identifier: NCT02397031     History of Changes
Other Study ID Numbers: IIBSP-MOD-2011-147
First Posted: March 24, 2015    Key Record Dates
Last Update Posted: March 25, 2015
Last Verified: March 2015

Keywords provided by Juan Carlos Pascual, Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau:
borderline personality disorder
mindfulness

Additional relevant MeSH terms:
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Disease
Personality Disorders
Borderline Personality Disorder
Pathologic Processes
Mental Disorders