Identification of Novel Molecular Markers for Cerebral Ischemia From Patients With Minor and Devastating Ischemic Injury
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|ClinicalTrials.gov Identifier: NCT02389647|
Recruitment Status : Active, not recruiting
First Posted : March 17, 2015
Last Update Posted : August 11, 2017
|Condition or disease|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||Identification of Novel Molecular Markers for Cerebral Ischemia From Patients With Minor and Devastating Ischemic Injury|
|Study Start Date :||March 2015|
|Estimated Primary Completion Date :||August 2018|
|Estimated Study Completion Date :||August 2018|
Subjects undergoing elective endovascular catheterization for coiling of unruptured cerebral aneurysms. Four blood draws of 5mL each: (1) prior to initiation of procedure; (2) at the time of catheterization of major cerebral vessels, (3) immediately after the procedure, and (4) 24-hours after the procedure.
Ischemic stroke group
Subjects who present to the emergency department with ischemic infarcts of <6 hours. Four blood draws of 5mL each: (1) at time of enrollment but prior to tPA, (2) 6 hours post-tPA, (3) 12 hours post-tPA, and (4) 24 hours post-tPA.
Subjects who present to the emergency department with intracranial hemorrhage. One 5mL blood draw within 24 hours of onset.
- Identification of biomarkers selective for ischemia of the central nervous system [ Time Frame: After each blood draw ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02389647
|United States, Arizona|
|St. Joseph's Hospital and Medical Center/Barrow Neurological Institute|
|Phoenix, Arizona, United States, 85013|
|Principal Investigator:||Peter Nakaji, MD||Saint Joseph's Hospital and Medical Center/Barrow Neurological Institute|