Acute Microvascular Changes With LDL Apheresis
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|ClinicalTrials.gov Identifier: NCT02388633|
Recruitment Status : Completed
First Posted : March 17, 2015
Last Update Posted : August 23, 2018
|Condition or disease||Intervention/treatment|
|Study Type :||Observational|
|Actual Enrollment :||8 participants|
|Actual Study Start Date :||March 1, 2015|
|Actual Primary Completion Date :||July 1, 2018|
|Actual Study Completion Date :||July 1, 2018|
Patients undergoing apheresis for elevated LDL. Patients will undergo contrast ultrasound perfusion imaging at rest and during forearm exercise at before and immediately after apheresis.
Clinically-indicated LDL apheresis
- Skeletal Muscle Perfusion at Rest [ Time Frame: 10 min ]Contrast ultrasound assessment of microvascular perfusion of forearm skeletal muscle
- Skeletal Muscle Perfusion at Rest [ Time Frame: 10 min ]Contrast ultrasound assessment of microvascular perfusion of forearm skeletal muscle during contractile exercise.
- RBC Deformability [ Time Frame: 10 min ]RBC deformability measured by elongation index.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02388633
|United States, Oregon|
|Oregon Health & Science University|
|Portland, Oregon, United States, 97239|
|Principal Investigator:||Jonathan Lindner, MD||OSHU|