Pleural Sliding During Valsalva and Muller Maneuvers (VALMUL)
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|ClinicalTrials.gov Identifier: NCT02386696|
Recruitment Status : Completed
First Posted : March 12, 2015
Last Update Posted : March 24, 2015
Recently, ultrasound artifacts mimicking lung sliding have been described in absence of the visceral pleura, in a group of patients who underwent pneumonectomy. In these patients, lung sliding was clearly absent during mechanical ventilation in the operated hemithorax. During spontaneous breathing, although of lower intensity compared to the unoperated hemithorax, some artifacts mimicking lung sliding and seashore sign were found during each deep spontaneous breath. These findings have led to the hypothesis that these artifacts may be due to the contraction of the intercostal muscles.
The objective of the present study is to reproduce such artifacts during contraction of the inspiratory and expiratory muscles with closed glottis (Valsalva and Muller maneuvers): in this condition each subject is not ventilating and the two pleural layers are not sliding one over each other.
|Condition or disease||Intervention/treatment||Phase|
|Pleural and Lung Ultrasound||Other: Ultrasound||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||20 participants|
|Intervention Model:||Single Group Assignment|
|Official Title:||Pleural Sliding and Contraction of Intercostal Muscles: Ultrasound Findings During Valsalva and Muller Maneuvers|
|Study Start Date :||January 2015|
|Actual Primary Completion Date :||February 2015|
|Actual Study Completion Date :||February 2015|
Experimental: Ultrasound findings
Thoracic ultrasound examinations in the following conditions:
Lung ultrasound examination on healthy volunteers
- lung ultrasound artifacts during contraction of the inspiratory and expiratory muscles with closed glottis (Valsalva and Muller maneuvers). [ Time Frame: 16 days ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02386696
|Principal Investigator:||Franco Cavaliere, M.D., Prof.||Institute of Anesthesia and Intensive Care Medicine, Catholic University of the Sacred Heart in Rome, Italy|