Study to Evaluate the Efficacy of N-acetylcysteine (NAC) in the Treatment of the Common Cold and Cough (NAC cold cough)
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Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled, Multiple-Dose, Proof-of-Concept Study to Evaluate the Efficacy of N-acetylcysteine Capsules in the Treatment of the Common Cold (Viral URTI) Associated With Cough in an Adult Population
Study Start Date
Actual Primary Completion Date
Actual Study Completion Date
Resource links provided by the National Library of Medicine
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Ages Eligible for Study:
18 Years to 65 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Cold/URTI symptoms occurring no more than 4 days
cough due to a cold or acute viral (URTI) with an onset of no more than 3 days
cough frequency with specified cut-off
A subchronic, or chronic cough (cough duration > 2 months) due to any condition other than a cold/URTI
Diagnosed as suffering from any pulmonary conditions associated with cough, e.g., chronic obstructive pulmonary disease (COPD), acute or chronic bronchitis, asthma, cystic fibrosis
Taking any medications known to induce cough
Fever of greater than 39°C (102°F) orally
Complication of the common cold like otitis media, severe sinusitis, or pneumonia
Other protocol-defined inclusion/exclusion criteria may apply