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Multispectral Imaging to Characterize Patterns of Vascular Supply Within Lymphoepithelial Mucosa in Oropharyngeal Cancer

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ClinicalTrials.gov Identifier: NCT02365844
Recruitment Status : Completed
First Posted : February 19, 2015
Last Update Posted : March 1, 2019
Sponsor:
Information provided by (Responsible Party):
Stanford University

Brief Summary:
The purpose of this study is to characterize the blood supply at the base of the tongue and within the tonsil region. We hypothesize that high-resolution Narrow Band Imaging (NBI) will improve the diagnosis of oropharyngeal carcinoma (OPC). The goal is to provide the better assessment of tumor and thus providing better preoperative expectations to patients with OPC or tumor extent prior to radiation therapy.

Condition or disease
Oropharyngeal Carcinoma Oropharynx Cancer

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Study Type : Observational
Actual Enrollment : 81 participants
Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Multispectral Imaging to Characterize Patterns of Vascular Supply Within the Lymphoepithelial Mucosa of Patients With Known or Suspected Oropharyngeal Carcinoma (OPC)
Actual Study Start Date : February 2015
Actual Primary Completion Date : August 27, 2018
Actual Study Completion Date : August 27, 2018

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. assessment of differential vascularity between normal and clinically apparent tumor with in the specified sites of oropharynx, using standard white-light endoscopy and narrow-band imaging [ Time Frame: 30 minutes ]
    endoscopy of the oropharynx using white-light and narrow-Band imaging



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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Stanford Cancer Center patients with oropharyngeal carcinoma
Criteria

Inclusion Criteria:

  • age 18 years or older
  • Written informed consent
  • Patients with oropharyngeal carcinoma

Exclusion Criteria:

  • Tumors of the oral cavity or nasopharynx

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02365844


Locations
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United States, California
Stanford University, School of Medicine
Stanford, California, United States, 95305
Sponsors and Collaborators
Stanford University
Investigators
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Principal Investigator: Chris Holsinger Stanford University

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Responsible Party: Stanford University
ClinicalTrials.gov Identifier: NCT02365844     History of Changes
Other Study ID Numbers: ENT0044
First Posted: February 19, 2015    Key Record Dates
Last Update Posted: March 1, 2019
Last Verified: February 2019

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Stanford University:
Narrow Band Imaging
oropharyngeal carcinoma
Additional relevant MeSH terms:
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Carcinoma
Oropharyngeal Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Pharyngeal Neoplasms
Otorhinolaryngologic Neoplasms
Head and Neck Neoplasms
Neoplasms by Site
Pharyngeal Diseases
Stomatognathic Diseases
Otorhinolaryngologic Diseases