GWAS Identified Susceptibility Loci for Glucocorticoid-induced FHN in the Chinese Population
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02365077|
Recruitment Status : Unknown
Verified February 2015 by xjpfW, Xijing Hospital.
Recruitment status was: Recruiting
First Posted : February 18, 2015
Last Update Posted : February 18, 2015
|Condition or disease|
|Femur Head Necrosis Adverse Effect of Glucocorticoids and Synthetic Analogues|
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||2500 participants|
|Observational Model:||Case Control|
|Target Follow-Up Duration:||1 Year|
|Official Title:||Genome-wide Association Study Identified Susceptibility Loci for Glucocorticoid-induced Femur Head Necrosis in the Chinese Population|
|Study Start Date :||January 2015|
|Estimated Primary Completion Date :||December 2018|
|Estimated Study Completion Date :||December 2018|
The patients of necrosis group was defined by a history of taking 1800 mg prednisolone or an equivalent over 4 week without the symptom of femur head necrosis after 1 year.
The patients of necrosis group was defined by a history of taking 1800 mg prednisolone or an equivalent over 4 week with the diagnosis of femur head necrosis.
- Glucocorticoid-induced femur head necrosis [ Time Frame: 1 year ]Hip joint MRI for the patients with a history of taking 1800 mg prednisolone or an equivalent over 4 week.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02365077
|Contact: Gang Gang, MD,PhDemail@example.com|
|Contact: Chen Yu|
|Xi'an, Shaanxi, China, 710032|
|Contact: Aidong Wen, MD 86-29-84771162|
|Principal Investigator: Gang Wang, M.D.|
|Sub-Investigator: Chen Yu, M.M.|