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The Impact of Improved WASH in Schools on Absence, Diarrhea and Helminth Infection in Lao PDR

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02342860
Recruitment Status : Completed
First Posted : January 21, 2015
Last Update Posted : May 6, 2019
Sponsor:
Collaborator:
UNICEF
Information provided by (Responsible Party):
Matthew Freeman, MPH, PhD, Emory University

Brief Summary:
The investigators will conduct a cluster-randomized trial to assess the impact of a school-based water, sanitation and hygiene program on health and educational outcomes of school children in Saravane Province, Laos. The intervention will include an improved water supply (borehole), a sanitation block that includes three pour-flush latrines with rainwater harvesting to be used for flushing and a urinal, and sinks for handwashing with soap. The school will also receive a facility for group handwashing (large pipe where many children can wash hands at once. United Nations International Children's Emergency Fund (UNICEF) will additionally provide behavior change education. Our key outcome of interest is pupil absence, which will be measured longitudinally using roll-call on days of schools visits. Secondary outcomes include self-reported absence, diarrhea and respiratory infection of a random selection of students. The investigators will also monitor the fidelity of the intervention and assess school conditions and pupil sanitation and handwashing behaviors using structured observation.

Condition or disease Intervention/treatment Phase
Hygiene Other: WASH in Schools (WinS) programme Not Applicable

Detailed Description:

Though limited, research suggests school-based water, sanitation and hygiene (WASH) improvements are capable of reducing pupil absence from 35-42%. However, few studies have rigorously evaluated the impact of comprehensive WASH in Schools (WinS) improvements on pupil absenteeism; to date, no research on the impact of WinS has been conducted in Lao PDR. This study will use longitudinal data collection to quantify the impact of UNICEF's WinS program on pupil learning and health in Lao People's Democratic Republic (Lao PDR).

Research activities will take place Saravane Province, Lao PDR. Schools are eligible if they are a primary, non-Community-Built Construction (CBC) school, and lacking WASH facilities. A total of 136 schools will be randomly selected from a pool of all eligible schools, and randomly assigned to either the intervention or comparison group (68 schools each). Directors of the selected schools will be contacted and informed about procedures prior to the start of the study, and they will provide permission to conduct the study at their schools if they so choose. At each school the investigators will randomly select up to 60 pupils in grades 1-5. Research staff will approach selected pupils at school to request informed oral assent for participation. The informed assent process and data collection will be conducted by local trained enumerators in the child's preferred language of Laotian or a local dialect. Oral rather than written assent was chosen due to varied literacy capabilities and to limit paperwork that identifies participants. A waiver of parental consent for pupil interviews has been secured from the Ministry of Education and Sports. At each school, school directors will be asked to sign in loco parentis ("in the place of parent") on behalf of the pupil participants.

Data collection will take place at each school once every six to eight weeks for the duration of up to three school years. The investigators will conduct school observations and an interview with the school director about school conditions, handwashing behavior observations of children, and a review of aggregate school-wide academic record data including percentage of children obtaining a passing average, advancing to the next class, and drop-outs. None of these school activities collect personal data or identifiers. Data collection with pupils will be done with the same pupils every six to eight weeks and will entail a five-minute interview asking about recent absence, symptoms of diarrhea or respiratory illness, age, and grade. Select pupils in a subset of schools will undergo testing for cognition, attention, and hydration. Select pupils in a subset of school will provide a stool sample for analyses of helminth infection prior to school-wide de-worming. Data collection will also take place at the household of select pupils in a subset of schools. The investigators will conduct a household survey once at the beginning of each school year to assess the range of household WASH access among pupils in study selected schools.

All data collection will occur at the school or the household, will be conducted by trained local enumerators, and will be stored on password-protected mobile data collection devices. Data will be uploaded to a password-protected server and will not contain personal identifying information, but rather a pupil identification . Enumerators will maintain a separate form that links identifications with names of pupils, which will be kept confidential. There are no direct benefits other than contribution to general knowledge that will inform future school WASH projects. There are no risks to participation other than a small amount of class time missed by pupils, and great efforts will be made to minimize time outside of class.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 8873 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Measuring the Impact of WASH in Schools in the Lao People's Democratic Republic
Study Start Date : September 2014
Actual Primary Completion Date : March 31, 2017
Actual Study Completion Date : March 31, 2017

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Diarrhea

Arm Intervention/treatment
Experimental: WASH in Schools (WinS) programme
Schools in the intervention group will receive the UNICEF/Department of Foreign Affairs and Trade (DFAT)-supported WinS programme that includes a new water supply, 3 latrines (boys, girls, handicapped), and handwashing facilities. It will also include behavior change education.
Other: WASH in Schools (WinS) programme

The intervention group will receive the UNICEF/DFAT-supported WinS programme, which consists of the following intervention package:

  • Hardware: water supply system, handwashing station for group handwashing, and gender-segregated toilets with one facility accessible to students with physical disabilities;
  • Software: operations and maintenance (O&M) training for teachers, hygiene training, and basic hygiene package.

No Intervention: Control
Schools in the control group will receive no additional WinS programming.



Primary Outcome Measures :
  1. Pupil absenteeism [ Time Frame: 20 months ]
    Rates of pupil absenteeism from school, measured through roll call, review of teacher records, and pupil self-report


Secondary Outcome Measures :
  1. Pupil educational attainment ( measured through review of school/teacher records) [ Time Frame: 20 months ]
    Enrollment, attrition, progression, and performance will be measured through review of school/teacher records

  2. Pupil health attainment (measured through pupil self-report) [ Time Frame: 20 months ]
    Diarrhea, respiratory infection, and conjunctivitis will be measured through pupil self-report; hydration will be measured through analysis of urine specific gravity; helminth prevalence and infection intensity will be measured through analysis of stool samples

  3. Behavior change (Handwashing behavior and proxy indicators of WASH facility usage will be measured using structured observation) [ Time Frame: 20 months ]
    Handwashing behavior and proxy indicators of WASH facility usage will be measured using structured observation; household and school WASH facility usage will be measured through pupil self-report



Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Schools must meet the following criteria to be eligible for inclusion in the study:

  • Located in the Saravane, Ta Oy, Toumlane, Lakhonepheng, Vapy, Khongsedone, Lao Ngam, and Samoui Districts
  • Non-Community-Based Construction (CBC) school
  • Primary school
  • Lacking functional WASH facilities
  • If part of a complex, no other schools in the complex have already been selected to participate in the study.

Pupils must meet the following criteria to be eligible for inclusion in the study:

  • Grades 3-5 in study selected schools
  • Understand and respond to study assent process

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02342860


Sponsors and Collaborators
Emory University
UNICEF
Investigators
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Principal Investigator: Matthew C Freeman, PhD, MPH Emory University
Publications of Results:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: Matthew Freeman, MPH, PhD, Assistant Professor, Emory University
ClinicalTrials.gov Identifier: NCT02342860    
Other Study ID Numbers: IRB00076404
First Posted: January 21, 2015    Key Record Dates
Last Update Posted: May 6, 2019
Last Verified: May 2019
Keywords provided by Matthew Freeman, MPH, PhD, Emory University:
Water
sanitation
hygiene access in school