Study of Circulating Microparticles in Giant Cell Arteritis (MicroGiant)
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ClinicalTrials.gov Identifier: NCT02333708
Recruitment Status : Unknown
Verified September 2016 by University Hospital, Caen. Recruitment status was: Recruiting
To demonstrate that microparticles (MPs), having a powerful procoagulant potential, are in larger amounts in the blood of patients with histologically proven giant cell arteritis (GCA), compared with patients matched for age, sex and with or without inflammatory syndrome.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
primary and secondary care hospital
For GCA group:
Men and women ≥ 18 years of age Patient affiliated to social security regimen
Informed and having signed the consent form to take part in the study.
Diagnosis of GCA, meeting at least 3 of the following 5 American College of Rheumatology (ACR) criteria for the diagnosis of GCA, including inflammatory syndrome and having
Either temporal artery biopsy showing characteristic GCA abnormality
Or inflammatory arteritis on imaging examination
Persons under protection of the court or guardianship
Inability to understand or to follow study procedures
cancer diagnosed within the previous 5 years (except for non-melanoma skin cancer or in situ carcinoma of the cervix)non-contributory or inconclusive temporal artery biopsy
Any conditions that might interfere with MPs level: diabetes, recent endo-arterial gesture, current treatment with corticosteroids.
Participation in another ongoing clinical trial Current anticoagulant therapy
Giant Cell Arteritis
Vasculitis, Central Nervous System
Autoimmune Diseases of the Nervous System
Nervous System Diseases
Central Nervous System Diseases
Skin Diseases, Vascular
Immune System Diseases
Connective Tissue Diseases