To Examine Whether or Not the Primary Causes of OA or RA Might be Bone Alterations
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|ClinicalTrials.gov Identifier: NCT02327650|
Recruitment Status : Recruiting
First Posted : December 30, 2014
Last Update Posted : November 22, 2018
Generally, osteoarthris (OA) is considered as primarily cartilage disease. However, as we and others have previously reported, a portion of OA might be caused primarily by bone alterations. In this study, we prospectively and retrospectively show that the bone altertations may affect OA primarily in all of the joints.
In addition, rheumatoid arthritis (RA) is a joint disease when immune system attacks synovium. Joint destruction occurrs continuously if suitable treatment is not performed. The etiology of RA is still largely unknown. As with OA, RA can be primarily damaged in bone, instead of cartilage. Here we prospectively and retrospectively show that the bone altertations may affect RA primarily in all of the joints.
|Condition or disease||Intervention/treatment|
|Progression of Rheumatoid Arthritis Osteoarthritis of Multiple Joints||Procedure: The examinations for bones in joints of OA and RA patients|
|Study Type :||Observational|
|Estimated Enrollment :||200 participants|
|Official Title:||The Examinations Whether or Not the Primary Causes of Osteoarthritis or Rheumatoid Arthritis in Joints Might be Bone Alterations|
|Study Start Date :||November 2015|
|Actual Primary Completion Date :||April 2016|
|Estimated Study Completion Date :||December 2019|
RA and OA
Every 2 or 3 months, plain radiograph, blood and urinary tests, and MRI are performed in the painful joints of RA.
Procedure: The examinations for bones in joints of OA and RA patients
- The bone signal changes detected by MRI in OA and/or RA patients [ Time Frame: 1 year ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02327650
|Matsumoto, Nagano, Japan, 3908621|
|Contact: Yukio Nakamura, MD, PhD +81-263-37-2659 email@example.com|
|Principal Investigator: Yukio Nakamura, MD, PhD|
|Contact: Yukio Nakamura firstname.lastname@example.org|