Evaluation of Progression of Diabetic Retinopathy With Rapid Correction of Hyperglycemia
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|ClinicalTrials.gov Identifier: NCT02326259|
Recruitment Status : Recruiting
First Posted : December 29, 2014
Last Update Posted : May 3, 2017
|Condition or disease||Intervention/treatment|
|Diabetic Retinopathy||Other: Initiation of treatment of diabetes|
The goal of this research is to conduct a study that investigates (1) how diabetic retinopathy progresses when poorly controlled Type 2 diabetic patients initiate intensive blood sugar control and (2) to determine if there are biomarkers that predict progression of diabetic retinopathy. Typically, the retina is thought to undergo rapid progression of diabetic retinopathy, although this has been poorly characterized in a formal study.
The first goal will be quantified by taking initial photos of the retina with the Pictor Plus hand-held fundus camera, as well as monthly photos (when the patient is scheduled for their endocrinology appointments, throughout a 90 day period). The second goal will be accomplished by testing the patient's blood. There will be an initial blood withdraw, as well as blood withdraws at monthly intervals throughout the same 90 day period as the fundus photos.
This study will help us to understand the pathogenesis of diabetic retinopathy, as well as potentially lead to an improved understanding of progression of diabetic retinopathy.
|Study Type :||Observational|
|Estimated Enrollment :||30 participants|
|Official Title:||Evaluation of Progression of Diabetic Retinopathy With Rapid Correction of Hyperglycemia|
|Study Start Date :||March 2015|
|Estimated Primary Completion Date :||March 2018|
|Estimated Study Completion Date :||March 2018|
- Other: Initiation of treatment of diabetes
Treatment of diabetes according to the standard of care.
- Progression of diabetic retinopathy [ Time Frame: 90 days ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02326259
|Contact: Ajay Rao, MDfirstname.lastname@example.org|
|Contact: William J Foster, MD, PhD||855-250-3937||DrFoster@WilliamFosterMD.com|
|United States, Pennsylvania|
|Philadelphia, Pennsylvania, United States, 19140|
|Contact: Martin Schardt, BS 215-707-3185 email@example.com|
|Contact: William J Foster, MD, PhD 215-707-3185 firstname.lastname@example.org|
|Principal Investigator:||William J Foster, MD, PhD||Temple University|
|Principal Investigator:||Ajay D Rao, MD, MMSc, FACP||Temple University|
|Principal Investigator:||Raul A DeLa Cadena, MD||Temple University|