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Physical Exercise and Pollution: Cardiorrespiratory, Cerebral and Molecular Aspects

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ClinicalTrials.gov Identifier: NCT02304731
Recruitment Status : Completed
First Posted : December 2, 2014
Last Update Posted : December 2, 2014
Sponsor:
Collaborator:
University of Sao Paulo
Information provided by (Responsible Party):
Luciana Caxa, Federal University of São Paulo

Brief Summary:
Modern society increasingly seeks healthy life style, and regular physical activity is considered one of the main factors that improve the quality of life. The evidence shows that the aerobic physical training in controlled environments benefit various aspects of human health, including cognition in the elderly population. However, when exercise is performed in a polluted environment, the individual is subjected to grater exposure to pollutants due to increased ventilation (breathing).

Condition or disease Intervention/treatment Phase
Cognitive Function 1, Social Other: Physical Exercise Phase 4

Detailed Description:
Modern society increasingly seeks healthy life style, and regular physical activity is considered one of the main factors that improve the quality of life. The evidence shows that the aerobic physical training in controlled environments benefit various aspects of human health, including cognition in the elderly population. However, when exercise is performed in a polluted environment, the individual is subjected to grater exposure to pollutants due to increased ventilation (breathing). It is well known that inhaled pollutants can cause oxidative modification in biomolecules and oxidative stress is a cause of diverse diseases. This scenario raises important questions: the deleterious effects of pollution can abolish the beneficial effects of exercise? This issue is currently relevant given the increasing level of air pollution in large urban centers such as Sao Paulo city and at the same time, outdoor physical activity in public places is largely stimulated by public organizations, particularly for elderly. Thus this multidisciplinary project aims to investigate the deleterious effects of urban air pollution in elderly people who practice aerobic physical exercise outdoors in Sao Paulo and compare with those who practice in Laboratory. This study can provide important knowledge for public health and welfare of the population.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 45 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: Physical Exercise and Pollution: Cardiorrespiratory, Cerebral and Molecular Aspects.
Study Start Date : February 2013
Actual Primary Completion Date : December 2013
Actual Study Completion Date : July 2014

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Exercise and Pollution Groups
Physical Exercise performed in a clean environment and in a polluted environment.
Other: Physical Exercise
Incremental running




Primary Outcome Measures :
  1. Cognitive Benefits [ Time Frame: 12 weeks ]
    Neuropsychological Tests applied at the beginning and at the end of protocol



Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria: Health Subjects that lives in São Paulo city for at least 10 years.

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Exclusion Criteria: Neuropsychological issues.

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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02304731


Sponsors and Collaborators
Federal University of São Paulo
University of Sao Paulo
Investigators
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Study Chair: Luciana Caxá, Master Federal University of Sao Paulo
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Responsible Party: Luciana Caxa, Master Degree, Federal University of São Paulo
ClinicalTrials.gov Identifier: NCT02304731    
Other Study ID Numbers: UFSao Paulo
First Posted: December 2, 2014    Key Record Dates
Last Update Posted: December 2, 2014
Last Verified: November 2014
Keywords provided by Luciana Caxa, Federal University of São Paulo:
Physical Exercise, Atmospheric Pollution, Cognition.