Corneal Lesions in Intensive Care Unit (ICU) Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care Center Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care Center (CORNEALPREV)
|ClinicalTrials.gov Identifier: NCT02293876|
Recruitment Status : Completed
First Posted : November 18, 2014
Last Update Posted : November 19, 2014
|Condition or disease||Intervention/treatment||Phase|
|Keratitis Corneal Ulcer||Device: LACRIBELL® Device: LIPOSIC® Device: Glad wrap||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||360 participants|
|Intervention Model:||Factorial Assignment|
|Official Title:||Risk for Corneal Injury in Critically Ill Patients and Effect of Nursing Interventions for Its Prevention: Randomized Controlled Trial|
|Study Start Date :||April 2013|
|Actual Primary Completion Date :||April 2014|
|Actual Study Completion Date :||November 2014|
Sham Comparator: Eye drop
Eye drop LACRIBELL® - two drops each eye, three times a day, after eye cleansing.
Hypromellose and dextran based eyedrop, used in the treatment of dry eye.
Other Name: Eyedrop
Sham Comparator: Ocular gel
Ocular gel LIPOSIC® applied three times a day at the lower palpebra from medium line to the lateral border.
Carbomer and Sorbitol based gel, used in the treatment of dry eye.
Other Name: Occular Gel
Sham Comparator: Glad wrap
Occlusion of the orbital area with a Glad wrap, turning the area into a moisture chamber.
Device: Glad wrap
A clear plastic wrap occluding eye and orbital area, turning the space into a moisture chamber.
Other Name: Polyethylene film
No Intervention: Control group
Ocular cleansing three times a day.
- Keratitis [ Time Frame: Five days ]Presence of keratitis visible with a cobalt light ophthalmoscope and fluorescein eye drop.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02293876
|Hospital Risoleta Tolentino Neves|
|Belo Horizonte, Minas Gerais, Brazil, 31744012|
|Principal Investigator:||Andreza Werli-Alvarenga, RN, MD, PhD||Hospital Risoleta Tolentino Neves|