The Role of Narrowband Ultraviolet B Exposure in the Maintenance of Vitamin D Levels During Winter
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|ClinicalTrials.gov Identifier: NCT02275650|
Recruitment Status : Completed
First Posted : October 27, 2014
Last Update Posted : October 27, 2014
|Condition or disease||Intervention/treatment||Phase|
|Vitamin D Deficiency||Radiation: nbUVB||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||37 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||The Role of Narrowband Ultraviolet B Exposure in the Maintenance of Vitamin D Levels During Winter|
|Study Start Date :||September 2013|
|Actual Primary Completion Date :||May 2014|
|Actual Study Completion Date :||May 2014|
2 SED dose of nbUVB will be given every other week for this intervention group.
2 SED nbUVB exposure will be given every other week
No Intervention: control
No nbUVB illumination will be given for the control group.
- 25(OH)D level [ Time Frame: up to 30 weeks ]Serum 25(OH)D levels were measured at the onset and at weeks 6, 14, 20, 26 and 30.
- CYP27A1 and CYP27B1 enzyme expression levels [ Time Frame: up to 14 weeks ]CYP27A1 and CYP27B1 enzyme expression levels will be analysed from 6mm punch biopsies at the onset and at week 14.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02275650
|Päijät-Häme Central Hospital|
|Lahti, Pirkanmaa, Finland, 15850|
|Tampere University Hospital|
|Tampere, Pirkanmaa, Finland, 33521|
|Principal Investigator:||Toni T Karppinen, MD||Päijänne Tavastia Central Hospital|
|Study Director:||Erna Snellman, professor||Tampere University Hospital|