Ultrasound Guided Thoracic Paravertebral Block for Hepatic Tumors Ablation
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT02271646|
Recruitment Status : Completed
First Posted : October 22, 2014
Last Update Posted : March 12, 2019
Patients undergo percutaneous radiofrequency ablation of hepatic tumors at Siriraj hospital normally receive only intravenous sedative drugs which sometimes can not provide effective pain control.
TPVB is suitable for unilateral operations. And it is increasing popular nowadays because of using ultrasound guided which make it is more reliable and has less side effects especially the severe one such as pneumothorax. To cover all nerve supply liver, we decided to use right TPVB at T5-6, T7-8, and T9-10.
The aim of this study is to prove that TPVB can provide an effective pain control for patients undergo liver RFA both at rest and movement (cough). We are going to measure the pain score at recovery room and the effective pain control means patients has mild pain (pain score less </= 3 and do not ask for analgesic drugs).
|Condition or disease||Intervention/treatment||Phase|
|Liver Cancer||Drug: 0.5% marcaine 20ml||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||35 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Ultrasound Guided Thoracic Paravertebral Blocks: An Effective Pain Control in Percutaneous Radiofrequency Ablation of Hepatic Tumors|
|Study Start Date :||August 2014|
|Actual Primary Completion Date :||March 2015|
|Actual Study Completion Date :||March 2015|
Experimental: 0.5% marcaine 20ml
3 levels ultrasound guided thoracic paravertebral blocks at T5-6, T7-8 and T9-10 (total 0.5% marcaine 20ml)
Drug: 0.5% marcaine 20ml
3 levels ultrasound guided thoracic paravertebral block at T5-6, T7-8 and T9-10 (total 0.5% marcaine 20ml)
- pain score at recovery room both at rest and movement (cough) [ Time Frame: Up to 24 hours ]All patients at recovery room has mild pain (pain score </= 3) and do not need any rescue analgesic drugs.
- Distribution of local anesthetic drugs after performing ultrasound guided TPVB at T5-6, T7-8 and T9-10. [ Time Frame: After performing TPVB at 5, 10, 20 and 30 minutes. ]Test with cold sensation.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02271646
|Bangkok, Thailand, 10700|
|Principal Investigator:||Pawinee Pangthipampai, M.D.||Mahidol University|